ICD-10 Code for Deficiency

The ICD-10-CM 2027 alphabetic index lists deficiency, deficient with the subterms below. More specific codes depend on the details documented, as listed in the official index (194 codes, 194 billable).

Index entries for Deficiency

3-beta hydroxysteroid dehydrogenase – E25.0
5-alpha reductase (with male pseudohermaphroditism) – E29.1
11-hydroxylase – E25.0
21-hydroxylase – E25.0
AADC (aromatic L-amino acid decarboxylase) – E70.81
ABCC6
- causing generalized arterial calcification of infancy – E83.823
- pseudoxanthoma elasticum – E83.824
abdominal muscle syndrome – Q79.4
accelerator globulin (Ac G) (blood) – D68.2
AC globulin (congenital) (hereditary) – D68.2
- acquired – D68.4
acid phosphatase – E83.39
acid sphingomyelinase (ASMD) – E75.249
- type
  - A – E75.240
  - A/B – E75.244
  - B – E75.241
activating factor (blood) – D68.2
ADA2 (adenosine deaminase 2) – D81.32
adenosine deaminase (ADA) – D81.30
- with severe combined immunodeficiency (SCID) – D81.31
- partial (type 1) – D81.39
- specified NEC – D81.39
- type 1 (without SCID) (without severe combined immunodeficiency) – D81.39
- type 2 – D81.32
aldolase (hereditary) – E74.19
alpha-1-antitrypsin – E88.01
amino-acids – E72.9
anemia – see Anemia
aneurin – E51.9
antibody with
- hyperimmunoglobulinemia – D80.6
- near-normal immunoglobins – D80.6
antidiuretic hormone – E23.2
anti-hemophilic
- factor (A) – D66
  - B – D67
  - C – D68.1
- globulin (AHG) – D66
antithrombin (antithrombin III) – D68.59
aromatic L-amino acid decarboxylase (AADC) – E70.81
ascorbic acid – E54
attention (disorder) (syndrome) – F98.8
- with hyperactivity – see Disorder, attention-deficit hyperactivity
autoprothrombin
- I – D68.2
- II – D67
- C – D68.2
beta-glucuronidase – E76.29
biotin – E53.8
biotin-dependent carboxylase – D81.819
biotinidase – D81.810
brancher enzyme (amylopectinosis) – E74.03
calciferol – E55.9
- with
  - adult osteomalacia – M83.8
  - rickets – see Rickets
calcium (dietary) – E58
calorie, severe – E43
- with marasmus – E41
  - and kwashiorkor – E42
cardiac – see Insufficiency, myocardial
carnitine – E71.40
- due to
  - hemodialysis – E71.43
  - inborn errors of metabolism – E71.42
  - Valproic acid therapy – E71.43
- iatrogenic – E71.43
- muscle palmityltransferase – E71.314
- primary – E71.41
- secondary – E71.448
carotene – E50.9
CD73 deficiency causing arterial calcification – E83.825
central nervous system – G96.89
ceruloplasmin (Wilson) – E83.01
choline – E53.8
Christmas factor – D67
chromium – E61.4
chronic neurovisceral acid sphingomyelinase – E75.244
chronic visceral acid sphingomyelinase – E75.241
clotting (blood) – D68.9 – see also Deficiency, coagulation factor
clotting factor NEC (hereditary) – D68.2 – see also Deficiency, factor
coagulation NOS – D68.9
- with
  - ectopic pregnancy – O08.1
  - molar pregnancy – O08.1
- acquired (any) – D68.4
- antepartum hemorrhage – see Hemorrhage, antepartum, with coagulation defect
- clotting factor NEC – D68.2 – see also Deficiency, factor
- due to
  - hyperprothrombinemia – D68.4
  - liver disease – D68.4
  - vitamin K deficiency – D68.4
- newborn, transient – P61.6
- postpartum – O72.3
- specified NEC – D68.8
cognitive – F09
color vision – H53.50
- achromatopsia – H53.51
- acquired – H53.52
- deuteranomaly – H53.53
- protanomaly – H53.54
- specified type NEC – H53.59
- tritanomaly – H53.55
combined glucocorticoid and mineralocorticoid – E27.49
contact factor – D68.2
copper (nutritional) – E61.0
corticoadrenal – E27.40
- primary – E27.1
craniofacial axis – Q75.009
cyanocobalamin – E53.8
C1 esterase inhibitor (C1-INH) – D84.1
debrancher enzyme (limit dextrinosis) – E74.03
dehydrogenase
- long chain/very long chain acyl CoA – E71.310
- medium chain acyl CoA – E71.311
- short chain acyl CoA – E71.312
diet – E63.9
dihydropyrimidine dehydrogenase (DPD) – E88.89
disaccharidase – E73.9
edema – see Malnutrition, severe
endocrine – E34.9
energy-supply – see Malnutrition
ENPP1
- causing
  - autosomal recessive hypophosphatemic rickets type 2 – E83.822
  - generalized arterial calcification of infancy – E83.821
enzymes, circulating NEC – E88.09
ergosterol – E55.9
- with
  - adult osteomalacia – M83.8
  - rickets – see Rickets
essential fatty acid (EFA) – E63.0
eye movements
- saccadic – H55.81
- smooth pursuit – H55.82
factor – see also Deficiency, coagulation
- Hageman – D68.2
- I (congenital) (hereditary) – D68.2
- II (congenital) (hereditary) – D68.2
- IX (congenital) (functional) (hereditary) (with functional defect) – D67
- multiple (congenital) – D68.8
  - acquired – D68.4
- V (congenital) (hereditary) – D68.2
- VII (congenital) (hereditary) – D68.2
- VIII (congenital) (functional) (hereditary) (with functional defect) – D66
  - with vascular defect – see Disease, von Willebrand
- X (congenital) (hereditary) – D68.2
- XI (congenital) (hereditary) – D68.1
- XII (congenital) (hereditary) – D68.2
- XIII (congenital) (hereditary) – D68.2
femoral, proximal focal (congenital) – see Defect, reduction, lower limb, longitudinal, femur
fibrin-stabilizing factor (congenital) (hereditary) – D68.2
- acquired – D68.4
fibrinase – D68.2
fibrinogen (congenital) (hereditary) – D68.2
- acquired – D65
folate – E53.8
folic acid – E53.8
foreskin – N47.3
fructokinase – E74.11
fructose 1,6-diphosphatase – E74.19
fructose-1-phosphate aldolase – E74.19
GABA (gamma aminobutyric acid) – E72.81
GABA-T (gamma aminobutyric acid transaminase) – E72.81
GABA transporter 1 – QA0.0131
galactokinase – E74.29
galactose-1-phosphate uridyl transferase – E74.29
gammaglobulin in blood – D80.1
- hereditary – D80.0
glass factor – D68.2
glucocorticoid – E27.49
- mineralocorticoid – E27.49
glucose-6-phosphatase – E74.01
glucose-6-phosphate dehydrogenase
- anemia – D55.0
- without anemia – D75.A
glucose transporter protein type 1 – E74.810
glucuronyl transferase – E80.5
Glut1 – E74.810
glycogen synthetase – E74.09
gonadotropin (isolated) – E23.0
growth hormone (idiopathic) (isolated) – E23.0
Hageman factor – D68.2
hemoglobin – D64.9
hepatophosphorylase – E74.09
homogentisate 1,2-dioxygenase – E70.29
hormone
- anterior pituitary (partial) – E23.0
  - growth – E23.0
- growth (isolated) – E23.0
- pituitary – E23.0
- testicular – E29.1
hypoxanthine- (guanine)-phosphoribosyltransferase (HG- PRT) (total H-PRT) – E79.1
immunity – D84.9
- cell-mediated – D84.89
  - with thrombocytopenia and eczema – D82.0
- combined – D81.9
- humoral – D80.9
- IgA (secretory) – D80.2
- IgG – D80.3
- IgM – D80.4
immuno – see Immunodeficiency
immunoglobulin, selective
- A (IgA) – D80.2
- G (IgG) (subclasses) – D80.3
- M (IgM) – D80.4
infantile neurovisceral acid sphingomyelinase – E75.240
inositol (B complex) – E53.8
intrinsic
- factor (congenital) – D51.0
- sphincter – N36.42
  - with urethral hypermobility – N36.43
iodine – E61.8
- congenital syndrome – see Syndrome, iodine-deficiency, congenital
iron – E61.1
- anemia – D50.9
kalium – E87.6
kappa-light chain – D80.8
labile factor (congenital) (hereditary) – D68.2
- acquired – D68.4
lacrimal fluid (acquired) – see also Syndrome, dry eye
- congenital – Q10.6
lactase
- congenital – E73.0
- secondary – E73.1
Laki-Lorand factor – D68.2
LCAD (long chain acyl CoA dehydrogenase deficiency) – E71.310
lecithin cholesterol acyltransferase – E78.6
leukocyte adhesion (LAD-I) (LAD-II) (LAD-III) – D71.1
- type I – D71.1
- type II – D71.1
- type III – D71.1
lipocaic – K86.89
lipoprotein (familial) (high density) – E78.6
liver phosphorylase – E74.09
lysosomal alpha-1, 4 glucosidase – E74.02
lysosome-associated membrane protein 2 [LAMP2] – E74.05
magnesium – E61.2
major histocompatibility complex
- class I – D81.6
- class II – D81.7
manganese – E61.3
MCAD (medium chain acyl CoA dehydrogenase deficiency) – E71.311
menadione (vitamin K) – E56.1
- newborn – P53
mental (familial) (hereditary) – see Disability, intellectual
methylenetetrahydrofolate reductase (MTHFR) – E72.12
mevalonate kinase – M04.1
mineral NEC – E61.8
mineralocorticoid – E27.49
- with glucocorticoid – E27.49
molybdenum (nutritional) – E61.5
moral – F60.2
multiple nutrient elements – E61.7
multiple sulfatase (MSD) – E75.26
muscle
- carnitine (palmityltransferase) – E71.314
- phosphofructokinase – E74.09
myoadenylate deaminase – E79.2
myocardial – see Insufficiency, myocardial
myophosphorylase – E74.04
NADH diaphorase or reductase (congenital) – D74.0
NADH-methemoglobin reductase (congenital) – D74.0
natrium – E87.1
niacin (amide) (-tryptophan) – E52
nicotinamide – E52
nicotinic acid – E52
number of teeth – see Anodontia
nutrient element – E61.9
- multiple – E61.7
- specified NEC – E61.8
nutrition, nutritional – E63.9 – see also Nutrition deficient
- sequelae – see Sequelae, nutritional deficiency
- specified NEC – E63.8
of interleukin 1 receptor antagonist [DIRA] – M04.8
ornithine transcarbamylase – E72.4
ovarian – E28.39
oxygen – see Anoxia
pantothenic acid – E53.8
parathyroid (gland) – E20.9
perineum (female) – N81.89
phenylalanine hydroxylase – E70.1
phosphoenolpyruvate carboxykinase – E74.4
phosphofructokinase – E74.19
phosphomannomutase – E74.818
phosphomannose isomerase – E74.818
phosphomannosyl mutase – E74.818
phosphorylase kinase, liver – E74.09
pituitary hormone (isolated) – E23.0
plasma thromboplastin
- antecedent (PTA) – D68.1
- component (PTC) – D67
plasminogen (type 1) (type 2) – E88.02
platelet NEC – D69.19
- constitutional – see Disease, von Willebrand
polyglandular – E31.8
- autoimmune – E31.0
potassium (K) – E87.6
prepuce – N47.3
proaccelerin (congenital) (hereditary) – D68.2
- acquired – D68.4
proconvertin factor (congenital) (hereditary) – D68.2
- acquired – D68.4
protein – E46 – see also Malnutrition
- anemia – D53.0
- C – D68.59
- S – D68.59
prothrombin (congenital) (heredItary) – D68.2
- acquired – D68.4
Prower factor – D68.2
pseudocholinesterase – E88.09
PTA (plasma thromboplastin antecedent) – D68.1
PTC (plasma thromboplastin component) – D67
purine nucleoside phosphorylase (PNP) – D81.5
pyracin (alpha) (beta) – E53.1
pyridoxal – E53.1
pyridoxamine – E53.1
pyridoxine (derivatives) – E53.1
pyruvate
- carboxylase – E74.4
- dehydrogenase – E74.4
riboflavin (vitamin B2) – E53.0
salt – E87.1
SCAD (short chain acyl CoA dehydrogenase deficiency) – E71.312
secretion
- ovary – E28.39
- salivary gland (any) – K11.7
- urine – R34
selenium (dietary) – E59
serum antitrypsin, familial – E88.01
short stature homeobox gene (SHOX)
- with
  - dyschondrosteosis – Q78.8
  - short stature (idiopathic) – E34.328
  - Turner's syndrome – Q96.9
sodium (Na) – E87.1
SPCA (factor VII) – D68.2
sphincter, intrinsic – N36.42
- with urethral hypermobility – N36.43
stable factor (congenital) (hereditary) – D68.2
- acquired – D68.4
Stuart-Prower (factor X) – D68.2
succinic semialdehyde dehydrogenase – E72.81
sucrase – E74.39
sulfatase – E75.26
sulfite oxidase – E72.19
thiamin, thiaminic (chloride) – E51.9
- beriberi (dry) – E51.11
  - wet – E51.12
thrombokinase – D68.2
- newborn – P53
thyroid (gland) – see Hypothyroidism
tocopherol – E56.0
tooth bud – K00.0
transcobalamine II (anemia) – D51.2
vanadium – E61.6
vascular – I99.9
vasopressin – E23.2
vertical ridge – K06.8
viosterol – see Deficiency, calciferol
vitamin (multiple) – E56.9
- A – E50.9
  - with
    - Bitot's spot (corneal) – E50.1
    - follicular keratosis – E50.8
    - keratomalacia – E50.4
    - manifestations NEC – E50.8
    - night blindness – E50.5
    - scar of cornea, xerophthalmic – E50.6
    - xeroderma – E50.8
    - xerophthalmia – E50.7
    - xerosis
      - conjunctival – E50.0
        and Bitot's spot – E50.1
      - cornea – E50.2
        and ulceration – E50.3
  - sequelae – E64.1
- B (complex) – E53.9
  - with
    - beriberi (dry) – E51.11
      - wet – E51.12
    - pellagra – E52
- B1 NOS – E51.9
  - beriberi (dry) – E51.11
    - with circulatory system manifestations – E51.11
    - wet – E51.12
- B12 – E53.8
- B2 (riboflavin) – E53.0
- B6 – E53.1
- C – E54
  - sequelae – E64.2
- D – E55.9
  - with
    - adult osteomalacia – M83.8
    - rickets – see Rickets
  - 25-hydroxylase – E83.32
- E – E56.0
- folic acid – E53.8
- G – E53.0
- group B – E53.9
  - specified NEC – E53.8
- H (biotin) – E53.8
- K – E56.1
  - of newborn – P53
- nicotinic – E52
- P – E56.8
- PP (pellagra-preventing) – E52
- specified NEC – E56.8
- thiamin – E51.9
  - beriberi – see Beriberi
VLCAD (very long chain acyl CoA dehydrogenase deficiency) – E71.310
von Willebrand factor
- partial quantitative – D68.01 – see also Disease, von Willebrand
- total quantitative – D68.03 – see also Disease, von Willebrand
zinc, dietary – E60

How to choose the right code

Start with the main term, then pick the indented subterm that matches the documentation (type, cause, site, laterality, episode of care). Always confirm the code in the tabular list: follow its Excludes1/Excludes2, “code first” and “use additional code” notes, and add a 7th character where required.

Source: CDC/NCHS ICD-10-CM FY2027 alphabetic index.