D80.0 – Hereditary hypogammaglobulinemia
ICD-10-CM 2027 diagnosis code · Certain disorders involving the immune mechanism
ICD-10-CM code
D80.0
- Code
D80.0(claims format:D800)- Description
- Hereditary hypogammaglobulinemia
- Billable
- Yes – valid for HIPAA-covered transactions
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- Block
- D80-D89 Certain disorders involving the immune mechanism
- Parent codes
- D80
Notes for D80.0
Applicable to:
- Autosomal recessive agammaglobulinemia (Swiss type)
- X-linked agammaglobulinemia [Bruton] (with growth hormone deficiency)
Notes inherited from parent codes
Instructional notes at a category or block level apply to every code below it.
Block D80-D89
Includes:
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1 (not coded here):
Excludes2 (not included here):
- human immunodeficiency virus [HIV] disease (B20)
Index terms for D80.0
Entries in the ICD-10-CM alphabetic index that lead to this code:
- Agammaglobulinemia, X-linked
- Agammaglobulinemia, hereditary
- Agammaglobulinemia, Swiss type
- Hypogammaglobulinemia, hereditary
- Bruton's X-linked agammaglobulinemia
- Agammaglobulinemia, Bruton's X-linked
- Agammaglobulinemia, autosomal recessive
- Agammaglobulinemia, congenital sex-linked
- Syndrome, antibody deficiency, congenital
- Absence, gamma globulin in blood, hereditary
- Immunodeficiency, autosomal recessive, Swiss type
- Deficiency, deficient, gammaglobulin in blood, hereditary
- Syndrome, antibody deficiency, agammaglobulinemic, hereditary
- Syndrome, antibody deficiency, hypogammaglobulinemic, hereditary
Related codes in D80
- D80.1 – Nonfamilial hypogammaglobulinemiaBillable
- D80.2 – Selective deficiency of immunoglobulin A [IgA]Billable
- D80.3 – Selective deficiency of immunoglobulin G [IgG] subclassesBillable
- D80.4 – Selective deficiency of immunoglobulin M [IgM]Billable
- D80.5 – Immunodeficiency with increased immunoglobulin M [IgM]Billable
- D80.6 – Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemiaBillable
- D80.7 – Transient hypogammaglobulinemia of infancyBillable
- D80.8 – Other immunodeficiencies with predominantly antibody defectsBillable
- D80.9 – Immunodeficiency with predominantly antibody defects, unspecifiedBillable
Frequently asked questions
What is ICD-10 code D80.0?
D80.0 is the ICD-10-CM code for hereditary hypogammaglobulinemia, in the block D80-D89 (Certain disorders involving the immune mechanism).
Is D80.0 a billable code?
Yes. D80.0 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.
What category does D80.0 belong to?
It belongs to category D80 – Immunodeficiency with predominantly antibody defects.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.