D80.1 – Nonfamilial hypogammaglobulinemia
ICD-10-CM 2027 diagnosis code · Certain disorders involving the immune mechanism
ICD-10-CM code
D80.1
- Code
D80.1(claims format:D801)- Description
- Nonfamilial hypogammaglobulinemia
- Billable
- Yes – valid for HIPAA-covered transactions
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- Block
- D80-D89 Certain disorders involving the immune mechanism
- Parent codes
- D80
Notes for D80.1
Applicable to:
- Agammaglobulinemia with immunoglobulin-bearing B-lymphocytes
- Common variable agammaglobulinemia [CVAgamma]
- Hypogammaglobulinemia NOS
Notes inherited from parent codes
Instructional notes at a category or block level apply to every code below it.
Block D80-D89
Includes:
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1 (not coded here):
Excludes2 (not included here):
- human immunodeficiency virus [HIV] disease (B20)
Index terms for D80.1
Entries in the ICD-10-CM alphabetic index that lead to this code:
- Agammaglobulinemia
- Hypogammaglobulinemia
- Absence, gamma globulin in blood
- Hypogammaglobulinemia, nonfamilial
- Agammaglobulinemia, common variable
- Deficiency, deficient, gammaglobulin in blood
- Arthritis, arthritic, in, hypogammaglobulinemia
- Syndrome, antibody deficiency, agammaglobulinemic
- Syndrome, antibody deficiency, hypogammaglobulinemic
- Agammaglobulinemia, with, immunoglobulin-bearing B-lymphocytes
- Disease, diseased, connective tissue, systemic, in, hypogammaglobulinemia
Related codes in D80
- D80.0 – Hereditary hypogammaglobulinemiaBillable
- D80.2 – Selective deficiency of immunoglobulin A [IgA]Billable
- D80.3 – Selective deficiency of immunoglobulin G [IgG] subclassesBillable
- D80.4 – Selective deficiency of immunoglobulin M [IgM]Billable
- D80.5 – Immunodeficiency with increased immunoglobulin M [IgM]Billable
- D80.6 – Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemiaBillable
- D80.7 – Transient hypogammaglobulinemia of infancyBillable
- D80.8 – Other immunodeficiencies with predominantly antibody defectsBillable
- D80.9 – Immunodeficiency with predominantly antibody defects, unspecifiedBillable
Frequently asked questions
What is ICD-10 code D80.1?
D80.1 is the ICD-10-CM code for nonfamilial hypogammaglobulinemia, in the block D80-D89 (Certain disorders involving the immune mechanism).
Is D80.1 a billable code?
Yes. D80.1 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.
What category does D80.1 belong to?
It belongs to category D80 – Immunodeficiency with predominantly antibody defects.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.