E72.53 – Primary hyperoxaluria

ICD-10-CM 2027 diagnosis code · Metabolic disorders

Non-billable header

ICD-10-CM code E72.53

Code: E72.53 (claims format: E7253)
Description: Primary hyperoxaluria
Billable: No – use a more specific code below
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 4. Endocrine, nutritional and metabolic diseases (E00-E89)
Block: E70-E88 Metabolic disorders
Parent codes: E72 › E72.5

Billable codes under E72.53

E72.53 is a header code and cannot be used on claims. Choose the most specific code:

E72.530 – Primary hyperoxaluria, type 1Billable
E72.538 – Other specified primary hyperoxaluriaBillable
E72.539 – Primary hyperoxaluria, unspecifiedBillable

Notes for E72.53

Applicable to:

Oxalosis
Oxaluria

Excludes1 (not coded here):

secondary hyperoxaluria (E72.54-)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

E72 – Other disorders of amino-acid metabolism

Excludes1 (not coded here):

disorders of:
aromatic amino-acid metabolism (E70.-)
branched-chain amino-acid metabolism (E71.0-E71.2)
fatty-acid metabolism (E71.3)
purine and pyrimidine metabolism (E79.-)
gout (M1A.-, M10.-)

Block E70-E88

Excludes1 (not coded here):

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Excludes2 (not included here):

Ehlers-Danlos syndromes (Q79.6-)

Index terms for E72.53

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in E72.5

E72.50 – Disorder of glycine metabolism, unspecifiedBillable
E72.51 – Non-ketotic hyperglycinemiaBillable
E72.52 – TrimethylaminuriaBillable
E72.54 – Secondary hyperoxaluriaHeader
E72.59 – Other disorders of glycine metabolismBillable

Frequently asked questions

What is ICD-10 code E72.53?

E72.53 is the ICD-10-CM code for primary hyperoxaluria, in the block E70-E88 (Metabolic disorders).

Is E72.53 a billable code?

No. E72.53 is a header code with more specific child codes; report one of the billable codes listed above.

What category does E72.53 belong to?

It belongs to category E72 – Other disorders of amino-acid metabolism.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.