E72 – Other disorders of amino-acid metabolism

ICD-10-CM 2027 diagnosis code · Metabolic disorders

Non-billable header

ICD-10-CM code E72

Code: E72 (claims format: E72)
Description: Other disorders of amino-acid metabolism
Billable: No – use a more specific code below
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 4. Endocrine, nutritional and metabolic diseases (E00-E89)
Block: E70-E88 Metabolic disorders

Billable codes under E72

E72 is a header code and cannot be used on claims. Choose the most specific code:

E72.0 – Disorders of amino-acid transportHeader (more codes below)
E72.1 – Disorders of sulfur-bearing amino-acid metabolismHeader (more codes below)
E72.2 – Disorders of urea cycle metabolismHeader (more codes below)
E72.3 – Disorders of lysine and hydroxylysine metabolismBillable
E72.4 – Disorders of ornithine metabolismBillable
E72.5 – Disorders of glycine metabolismHeader (more codes below)
E72.8 – Other specified disorders of amino-acid metabolismHeader (more codes below)
E72.9 – Disorder of amino-acid metabolism, unspecifiedBillable

Notes for E72

Excludes1 (not coded here):

disorders of:
aromatic amino-acid metabolism (E70.-)
branched-chain amino-acid metabolism (E71.0-E71.2)
fatty-acid metabolism (E71.3)
purine and pyrimidine metabolism (E79.-)
gout (M1A.-, M10.-)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Block E70-E88

Excludes1 (not coded here):

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Excludes2 (not included here):

Ehlers-Danlos syndromes (Q79.6-)

Frequently asked questions

What is ICD-10 code E72?

E72 is the ICD-10-CM code for other disorders of amino-acid metabolism, in the block E70-E88 (Metabolic disorders).

Is E72 a billable code?

No. E72 is a header code with more specific child codes; report one of the billable codes listed above.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.