E72.20 – Disorder of urea cycle metabolism, unspecified

ICD-10-CM 2027 diagnosis code · Metabolic disorders

Billable code

ICD-10-CM code E72.20

Code: E72.20 (claims format: E7220)
Description: Disorder of urea cycle metabolism, unspecified
Billable: Yes – valid for HIPAA-covered transactions
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 4. Endocrine, nutritional and metabolic diseases (E00-E89)
Block: E70-E88 Metabolic disorders
Parent codes: E72 › E72.2

Notes for E72.20

Applicable to:

Hyperammonemia

Excludes1 (not coded here):

hyperammonemia-hyperornithinemia-homocitrullinemia syndrome E72.4
transient hyperammonemia of newborn (P74.6)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

E72 – Other disorders of amino-acid metabolism

Excludes1 (not coded here):

disorders of:
aromatic amino-acid metabolism (E70.-)
branched-chain amino-acid metabolism (E71.0-E71.2)
fatty-acid metabolism (E71.3)
purine and pyrimidine metabolism (E79.-)
gout (M1A.-, M10.-)

E72.2 – Disorders of urea cycle metabolism

Excludes1 (not coded here):

disorders of ornithine metabolism (E72.4)

Block E70-E88

Excludes1 (not coded here):

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Excludes2 (not included here):

Ehlers-Danlos syndromes (Q79.6-)

Index terms for E72.20

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in E72.2

E72.21 – ArgininemiaBillable
E72.22 – Arginosuccinic aciduriaBillable
E72.23 – CitrullinemiaBillable
E72.29 – Other disorders of urea cycle metabolismBillable

Frequently asked questions

What is ICD-10 code E72.20?

E72.20 is the ICD-10-CM code for disorder of urea cycle metabolism, unspecified, in the block E70-E88 (Metabolic disorders).

Is E72.20 a billable code?

Yes. E72.20 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does E72.20 belong to?

It belongs to category E72 – Other disorders of amino-acid metabolism.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.