E80 – Disorders of porphyrin and bilirubin metabolism

ICD-10-CM 2027 diagnosis code · Metabolic disorders

Non-billable header

ICD-10-CM code E80

Code: E80 (claims format: E80)
Description: Disorders of porphyrin and bilirubin metabolism
Billable: No – use a more specific code below
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 4. Endocrine, nutritional and metabolic diseases (E00-E89)
Block: E70-E88 Metabolic disorders

Billable codes under E80

E80 is a header code and cannot be used on claims. Choose the most specific code:

E80.0 – Hereditary erythropoietic porphyriaBillable
E80.1 – Porphyria cutanea tardaBillable
E80.2 – Other and unspecified porphyriaHeader (more codes below)
E80.3 – Defects of catalase and peroxidaseBillable
E80.4 – Gilbert syndromeBillable
E80.5 – Crigler-Najjar syndromeBillable
E80.6 – Other disorders of bilirubin metabolismBillable
E80.7 – Disorder of bilirubin metabolism, unspecifiedBillable

Notes for E80

Includes:

defects of catalase and peroxidase

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Block E70-E88

Excludes1 (not coded here):

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Excludes2 (not included here):

Ehlers-Danlos syndromes (Q79.6-)

Frequently asked questions

What is ICD-10 code E80?

E80 is the ICD-10-CM code for disorders of porphyrin and bilirubin metabolism, in the block E70-E88 (Metabolic disorders).

Is E80 a billable code?

No. E80 is a header code with more specific child codes; report one of the billable codes listed above.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.