C49.8 – Malignant neoplasm of overlapping sites of connective and soft tissue

ICD-10-CM 2027 diagnosis code · Malignant neoplasms of mesothelial and soft tissue

Billable code

ICD-10-CM code C49.8
Code
C49.8 (claims format: C498)
Description
Malignant neoplasm of overlapping sites of connective and soft tissue
Short description
Malignant neoplasm of ovrlp sites of conn and soft tissue
Billable
Yes – valid for HIPAA-covered transactions
Valid for
Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter
2. Neoplasms (C00-D49)
Block
C45-C49 Malignant neoplasms of mesothelial and soft tissue
Parent codes
C49

Notes for C49.8

Applicable to:
  • Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

C49 – Malignant neoplasm of other connective and soft tissue

Includes:
  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)
Excludes1 (not coded here):
  • malignant neoplasm of cartilage (of):
  • articular (C40-C41)
  • larynx (C32.3)
  • nose (C30.0)
  • malignant neoplasm of connective tissue of breast (C50.-)
Excludes2 (not included here):
  • Kaposi's sarcoma of soft tissue (C46.1)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • malignant neoplasm of peritoneum (C48.2)
  • malignant neoplasm of retroperitoneum (C48.0)
  • malignant neoplasm of uterine ligament (C57.3)
  • mesothelioma (C45.-)

Related codes in C49

Frequently asked questions

What is ICD-10 code C49.8?

C49.8 is the ICD-10-CM code for malignant neoplasm of overlapping sites of connective and soft tissue, in the block C45-C49 (Malignant neoplasms of mesothelial and soft tissue).

Is C49.8 a billable code?

Yes. C49.8 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does C49.8 belong to?

It belongs to category C49 – Malignant neoplasm of other connective and soft tissue.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.