M1415 – Patients who did not have a positive pd-l1 biomarker expression test result prior to the initiation of first-line immune checkpoint inhibitor therapy

HCPCS Level II code · M codes: Medical Services and Quality Measures

Active code Carrier judgment

HCPCS codeM1415
Long description
Patients who did not have a positive pd-l1 biomarker expression test result prior to the initiation of first-line immune checkpoint inhibitor therapy
Short description
No pos pdl1 bef ici ther
Pricing indicator
00 Not separately priced by Part B (bundled, not covered or Part A only)
Medicare coverage
C Carrier judgment – coverage decided by the Medicare contractor
BETOS category
Z2 Undefined codes
Added
January 1, 2025
Last change
January 1, 2025 – No change

Frequently asked questions

What is HCPCS code M1415?

M1415 is a HCPCS Level II code for patients who did not have a positive pd-l1 biomarker expression test result prior to the initiation of first-line immune checkpoint inhibitor therapy.

Does Medicare cover M1415?

The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.

Nearby M codes

Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.