M1414 – Documentation of medical reason(s) for not performing the pd-l1 biomarker expression test prior to initiation of first-line immune checkpoint inhibitor therapy (e.g., patient is in an urgent or emergent situation where delay of treatment would jeopardize the patient's health status; other medical reasons/contraindication)

HCPCS Level II code · M codes: Medical Services and Quality Measures

Active code Carrier judgment

HCPCS codeM1414
Long description
Documentation of medical reason(s) for not performing the pd-l1 biomarker expression test prior to initiation of first-line immune checkpoint inhibitor therapy (e.g., patient is in an urgent or emergent situation where delay of treatment would jeopardize the patient's health status; other medical reasons/contraindication)
Short description
Med rsn no pdl1 bef 1st ther
Pricing indicator
00 Not separately priced by Part B (bundled, not covered or Part A only)
Medicare coverage
C Carrier judgment – coverage decided by the Medicare contractor
BETOS category
Z2 Undefined codes
Added
January 1, 2025
Last change
January 1, 2025 – No change

Frequently asked questions

What is HCPCS code M1414?

M1414 is a HCPCS Level II code for documentation of medical reason(s) for not performing the pd-l1 biomarker expression test prior to initiation of first-line immune checkpoint inhibitor therapy (e.g., patient is in an urgent or emergent situation where delay of treatment would jeopardize the patient's health status; other medical reasons/contraindication).

Does Medicare cover M1414?

The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.

Nearby M codes

Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.