M1412 – Patients with metastatic nsclc with epidermal growth factor receptor (egfr) mutations, alk genomic tumor aberrations, or other targetable genomic abnormalities with approved first-line targeted therapy, such as nsclc with ros1 rearrangement, braf v600e mutation, ntrk 1/2/3 gene fusion, met ex14 skipping mutation, and ret rearrangement

HCPCS Level II code · M codes: Medical Services and Quality Measures

Active code Carrier judgment

HCPCS codeM1412
Long description
Patients with metastatic nsclc with epidermal growth factor receptor (egfr) mutations, alk genomic tumor aberrations, or other targetable genomic abnormalities with approved first-line targeted therapy, such as nsclc with ros1 rearrangement, braf v600e mutation, ntrk 1/2/3 gene fusion, met ex14 skipping mutation, and ret rearrangement
Short description
Met nsclc w/ egfr alk oth ab
Pricing indicator
00 Not separately priced by Part B (bundled, not covered or Part A only)
Medicare coverage
C Carrier judgment – coverage decided by the Medicare contractor
BETOS category
Z2 Undefined codes
Added
January 1, 2025
Last change
January 1, 2025 – No change

Frequently asked questions

What is HCPCS code M1412?

M1412 is a HCPCS Level II code for patients with metastatic nsclc with epidermal growth factor receptor (egfr) mutations, alk genomic tumor aberrations, or other targetable genomic abnormalities with approved first-line targeted therapy, such as nsclc with ros1 rearrangement, braf v600e mutation, ntrk 1/2/3 gene fusion, met ex14 skipping mutation, and ret rearrangement.

Does Medicare cover M1412?

The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.

Nearby M codes

Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.