Z17.31 – Human epidermal growth factor receptor 2 positive status

ICD-10-CM 2027 diagnosis code · Estrogen, and other hormones and factors receptor status (Z17)

Billable code

ICD-10-CM code Z17.31

Code: Z17.31 (claims format: Z1731)
Description: Human epidermal growth factor receptor 2 positive status
Billable: Yes – valid for HIPAA-covered transactions
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 21. Factors influencing health status and contact with health services (Z00-Z99)
Block: Z17 Estrogen, and other hormones and factors receptor status (Z17)
Parent codes: Z17 › Z17.3

Notes for Z17.31

Applicable to:

HER2+

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Z17 – Estrogen, and other hormones and factors receptor status

Code first:

malignant neoplasm, such as:
malignant neoplasm of breast (C50.-)
malignant neoplasm of ovary (C56.-)

Notes:

Use one code, as available, for each receptor: Z17.0, Z17.1, Z17.2-, Z17.3-

Index terms for Z17.31

Entries in the ICD-10-CM alphabetic index that lead to this code:

Status, human epidermal growth factor 2 receptor, positive

Related codes in Z17.3

Z17.32 – Human epidermal growth factor receptor 2 negative statusBillable

Frequently asked questions

What is ICD-10 code Z17.31?

Z17.31 is the ICD-10-CM code for human epidermal growth factor receptor 2 positive status, in the block Z17 (Estrogen, and other hormones and factors receptor status (Z17)).

Is Z17.31 a billable code?

Yes. Z17.31 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does Z17.31 belong to?

It belongs to category Z17 – Estrogen, and other hormones and factors receptor status.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.