Z15.81 – Genetic susceptibility to multiple endocrine neoplasia [MEN]

ICD-10-CM 2027 diagnosis code · Genetic carrier and genetic susceptibility to disease

Billable code

ICD-10-CM code Z15.81

Code: Z15.81 (claims format: Z1581)
Description: Genetic susceptibility to multiple endocrine neoplasia [MEN]
Billable: Yes – valid for HIPAA-covered transactions
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 21. Factors influencing health status and contact with health services (Z00-Z99)
Block: Z14-Z15 Genetic carrier and genetic susceptibility to disease
Parent codes: Z15 › Z15.8

Notes for Z15.81

Excludes1 (not coded here):

multiple endocrine neoplasia [MEN] syndromes (E31.2-)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Z15 – Genetic susceptibility to disease

Includes:

confirmed abnormal gene

Excludes1 (not coded here):

chromosomal anomalies (Q90-Q99)

Use additional code:

code, if applicable, for any associated family history of the disease (Z80-Z84)

Index terms for Z15.81

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in Z15.8

Z15.89 – Genetic susceptibility to other diseaseBillable

Frequently asked questions

What is ICD-10 code Z15.81?

Z15.81 is the ICD-10-CM code for genetic susceptibility to multiple endocrine neoplasia [MEN], in the block Z14-Z15 (Genetic carrier and genetic susceptibility to disease).

Is Z15.81 a billable code?

Yes. Z15.81 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does Z15.81 belong to?

It belongs to category Z15 – Genetic susceptibility to disease.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.