NPI Atlas

Z15 – Genetic susceptibility to disease

ICD-10-CM 2027 diagnosis code · Genetic carrier and genetic susceptibility to disease

Non-billable header

ICD-10-CM code Z15

Code: Z15 (claims format: Z15)
Description: Genetic susceptibility to disease
Billable: No – use a more specific code below
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 21. Factors influencing health status and contact with health services (Z00-Z99)
Block: Z14-Z15 Genetic carrier and genetic susceptibility to disease

Billable codes under Z15

Z15 is a header code and cannot be used on claims. Choose the most specific code:

Z15.0 – Genetic susceptibility to malignant neoplasmHeader (more codes below)
Z15.1 – Genetic susceptibility to epilepsy and neurodevelopmental disordersBillable
Z15.2 – Genetic susceptibility to obesityBillable
Z15.3 – Genetic susceptibility to kidney diseaseBillable
Z15.8 – Genetic susceptibility to other diseaseHeader (more codes below)

Notes for Z15

Includes:

confirmed abnormal gene

Excludes1 (not coded here):

chromosomal anomalies (Q90-Q99)

Use additional code:

code, if applicable, for any associated family history of the disease (Z80-Z84)

Frequently asked questions

What is ICD-10 code Z15?

Z15 is the ICD-10-CM code for genetic susceptibility to disease, in the block Z14-Z15 (Genetic carrier and genetic susceptibility to disease).

Is Z15 a billable code?

No. Z15 is a header code with more specific child codes; report one of the billable codes listed above.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.