R85.610 – Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)

ICD-10-CM 2027 diagnosis code · Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

Billable code

ICD-10-CM code R85.610
Code
R85.610 (claims format: R85610)
Description
Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)
Short description
Atyp squam cell of undet signfc cyto smr anus (ASC-US)
Billable
Yes – valid for HIPAA-covered transactions
Valid for
Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter
18. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Block
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
Parent codes
R85 › R85.6 › R85.61

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

R85 – Abnormal findings in specimens from digestive organs and abdominal cavity

Includes:
  • abnormal findings in peritoneal fluid
  • abnormal findings in saliva
Excludes1 (not coded here):
  • cloudy peritoneal dialysis effluent (R88.0)
  • fecal abnormalities (R19.5)

R85.61 – Abnormal cytologic smear of anus

Excludes1 (not coded here):
  • abnormal cytological findings in specimens from other digestive organs and abdominal cavity (R85.69)
  • carcinoma in situ of anus (histologically confirmed) (D01.3)
  • anal intraepithelial neoplasia I [AIN I] (K62.82)
  • anal intraepithelial neoplasia II [AIN II] (K62.82)
  • anal intraepithelial neoplasia III [AIN III] (D01.3)
  • dysplasia (mild) (moderate) of anus (histologically confirmed) (K62.82)
  • severe dysplasia of anus (histologically confirmed) (D01.3)
Excludes2 (not included here):
  • anal high risk human papillomavirus (HPV) DNA test positive (R85.81)
  • anal low risk human papillomavirus (HPV) DNA test positive (R85.82)

Block R83-R89

Excludes1 (not coded here):
  • abnormal findings on antenatal screening of mother (O28.-)
  • diagnostic abnormal findings classified elsewhere - see Alphabetical Index
Excludes2 (not included here):
  • abnormal findings on examination of blood, without diagnosis (R70-R79)
  • abnormal findings on examination of urine, without diagnosis (R80-R82)
  • abnormal tumor markers (R97.-)

Index terms for R85.610

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in R85.61

Frequently asked questions

What is ICD-10 code R85.610?

R85.610 is the ICD-10-CM code for atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US), in the block R83-R89 (Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis).

Is R85.610 a billable code?

Yes. R85.610 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does R85.610 belong to?

It belongs to category R85 – Abnormal findings in specimens from digestive organs and abdominal cavity.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.