R85.81 – Anal high risk human papillomavirus (HPV) DNA test positive

ICD-10-CM 2027 diagnosis code · Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

Billable code

ICD-10-CM code R85.81

Code: R85.81 (claims format: R8581)
Description: Anal high risk human papillomavirus (HPV) DNA test positive
Billable: Yes – valid for HIPAA-covered transactions
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 18. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Block: R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
Parent codes: R85 › R85.8

Notes for R85.81

Excludes1 (not coded here):

anogenital warts due to human papillomavirus (HPV) (A63.0)
condyloma acuminatum (A63.0)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

R85 – Abnormal findings in specimens from digestive organs and abdominal cavity

Includes:

abnormal findings in peritoneal fluid
abnormal findings in saliva

Excludes1 (not coded here):

cloudy peritoneal dialysis effluent (R88.0)
fecal abnormalities (R19.5)

Block R83-R89

Excludes1 (not coded here):

abnormal findings on antenatal screening of mother (O28.-)
diagnostic abnormal findings classified elsewhere - see Alphabetical Index

Excludes2 (not included here):

abnormal findings on examination of blood, without diagnosis (R70-R79)
abnormal findings on examination of urine, without diagnosis (R80-R82)
abnormal tumor markers (R97.-)

Index terms for R85.81

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in R85.8

Frequently asked questions

What is ICD-10 code R85.81?

R85.81 is the ICD-10-CM code for anal high risk human papillomavirus (HPV) DNA test positive, in the block R83-R89 (Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis).

Is R85.81 a billable code?

Yes. R85.81 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does R85.81 belong to?

It belongs to category R85 – Abnormal findings in specimens from digestive organs and abdominal cavity.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.