R65.20 – Severe sepsis without septic shock
ICD-10-CM 2027 diagnosis code · General symptoms and signs
ICD-10-CM code
R65.20
- Code
R65.20(claims format:R6520)- Description
- Severe sepsis without septic shock
- Billable
- Yes – valid for HIPAA-covered transactions
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 18. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
- Block
- R50-R69 General symptoms and signs
- Parent codes
- R65 › R65.2
Notes for R65.20
Applicable to:
- Severe sepsis NOS
Notes inherited from parent codes
Instructional notes at a category or block level apply to every code below it.
R65.2 – Severe sepsis
Applicable to:
- Infection with associated acute organ dysfunction
- Sepsis with acute organ dysfunction
- Sepsis with multiple organ dysfunction
- Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
Code first:
- underlying infection, such as:
- infection following a procedure (T81.4-)
- infections following infusion, transfusion and therapeutic injection (T80.2-)
- puerperal sepsis (O85)
- sepsis following complete or unspecified spontaneous abortion (O03.87)
- sepsis following ectopic and molar pregnancy (O08.82)
- sepsis following incomplete spontaneous abortion (O03.37)
- sepsis following (induced) termination of pregnancy (O04.87)
- sepsis NOS (A41.9)
Use additional code:
- code to identify specific acute organ dysfunction, such as:
- acute kidney failure (N17.-)
- acute respiratory failure (J96.0-)
- critical illness myopathy (G72.81)
- critical illness polyneuropathy (G62.81)
- disseminated intravascular coagulopathy [DIC] (D65)
- encephalopathy (metabolic) (septic) (G93.41)
- hepatic failure (K72.0-)
Index terms for R65.20
Entries in the ICD-10-CM alphabetic index that lead to this code:
Related codes in R65.2
Frequently asked questions
What is ICD-10 code R65.20?
R65.20 is the ICD-10-CM code for severe sepsis without septic shock, in the block R50-R69 (General symptoms and signs).
Is R65.20 a billable code?
Yes. R65.20 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.
What category does R65.20 belong to?
It belongs to category R65 – Symptoms and signs specifically associated with systemic inflammation and infection.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.