D84.81 – Immunodeficiency due to conditions classified elsewhere

ICD-10-CM 2027 diagnosis code · Certain disorders involving the immune mechanism

Billable code

ICD-10-CM code D84.81

Code: D84.81 (claims format: D8481)
Description: Immunodeficiency due to conditions classified elsewhere
Billable: Yes – valid for HIPAA-covered transactions
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Block: D80-D89 Certain disorders involving the immune mechanism
Parent codes: D84 › D84.8

Notes for D84.81

Excludes1 (not coded here):

certain disorders involving the immune mechanism (D80-D83, D84.0, D84.1, D84.9)
human immunodeficiency virus [HIV] disease (B20)

Code first:

underlying condition, such as:
chromosomal abnormalities (Q90-Q99)
diabetes mellitus (E08-E13)
malignant neoplasms (C00-C96)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Block D80-D89

Includes:

defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis

Excludes1 (not coded here):

autoimmune disease (systemic) NOS (M35.9)
functional disorders of polymorphonuclear neutrophils (D71-)

Excludes2 (not included here):

human immunodeficiency virus [HIV] disease (B20)

Index terms for D84.81

Entries in the ICD-10-CM alphabetic index that lead to this code:

Immunodeficiency, due to, conditions classified elsewhere

Related codes in D84.8

Frequently asked questions

What is ICD-10 code D84.81?

D84.81 is the ICD-10-CM code for immunodeficiency due to conditions classified elsewhere, in the block D80-D89 (Certain disorders involving the immune mechanism).

Is D84.81 a billable code?

Yes. D84.81 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does D84.81 belong to?

It belongs to category D84 – Other immunodeficiencies.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.