D57 – Sickle-cell disorders
ICD-10-CM 2027 diagnosis code · Hemolytic anemias
ICD-10-CM code
D57
- Code
D57(claims format:D57)- Description
- Sickle-cell disorders
- Billable
- No – use a more specific code below
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- Block
- D55-D59 Hemolytic anemias
Billable codes under D57
D57 is a header code and cannot be used on claims. Choose the most specific code:
- D57.0 – Hb-SS disease with crisisHeader (more codes below)
- D57.1 – Sickle-cell disease without crisisBillable
- D57.2 – Sickle-cell/Hb-C diseaseHeader (more codes below)
- D57.3 – Sickle-cell traitBillable
- D57.4 – Sickle-cell thalassemiaHeader (more codes below)
- D57.8 – Other sickle-cell disordersHeader (more codes below)
Notes for D57
Excludes1 (not coded here):
- other hemoglobinopathies (D58.-)
Use additional code:
- code for any associated fever (R50.81)
Index terms for D57
Entries in the ICD-10-CM alphabetic index that lead to this code:
- Nephropathy, sickle-cell
- Disorder, glomerular, sickle-cell disorders
- Retinopathy, proliferative NEC, sickle-cell
- Arthropathy, gouty, in, sickle-cell disorders
- Glomerulonephritis, in, sickle-cell disorders
- Retinopathy, in, sickle-cell disorders, proliferative
- Retinopathy, in, sickle-cell disorders, nonproliferative
Frequently asked questions
What is ICD-10 code D57?
D57 is the ICD-10-CM code for sickle-cell disorders, in the block D55-D59 (Hemolytic anemias).
Is D57 a billable code?
No. D57 is a header code with more specific child codes; report one of the billable codes listed above.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.