D57.81 – Other sickle-cell disorders with crisis
ICD-10-CM 2027 diagnosis code · Hemolytic anemias
ICD-10-CM code
D57.81
- Code
D57.81(claims format:D5781)- Description
- Other sickle-cell disorders with crisis
- Billable
- No – use a more specific code below
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- Block
- D55-D59 Hemolytic anemias
- Parent codes
- D57 › D57.8
Billable codes under D57.81
D57.81 is a header code and cannot be used on claims. Choose the most specific code:
- D57.811 – Other sickle-cell disorders with acute chest syndromeBillable
- D57.812 – Other sickle-cell disorders with splenic sequestrationBillable
- D57.813 – Other sickle-cell disorders with cerebral vascular involvementBillable
- D57.814 – Other sickle-cell disorders with dactylitisBillable
- D57.818 – Other sickle-cell disorders with crisis with other specified complicationBillable
- D57.819 – Other sickle-cell disorders with crisis, unspecifiedBillable
Notes inherited from parent codes
Instructional notes at a category or block level apply to every code below it.
D57 – Sickle-cell disorders
Excludes1 (not coded here):
- other hemoglobinopathies (D58.-)
Use additional code:
- code for any associated fever (R50.81)
D57.8 – Other sickle-cell disorders
Applicable to:
- Hb-SD disease
- Hb-SE disease
Related codes in D57.8
Frequently asked questions
What is ICD-10 code D57.81?
D57.81 is the ICD-10-CM code for other sickle-cell disorders with crisis, in the block D55-D59 (Hemolytic anemias).
Is D57.81 a billable code?
No. D57.81 is a header code with more specific child codes; report one of the billable codes listed above.
What category does D57.81 belong to?
It belongs to category D57 – Sickle-cell disorders.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.