D56.4 – Hereditary persistence of fetal hemoglobin [HPFH]
ICD-10-CM 2027 diagnosis code · Hemolytic anemias
ICD-10-CM code
D56.4
- Code
D56.4(claims format:D564)- Description
- Hereditary persistence of fetal hemoglobin [HPFH]
- Billable
- Yes – valid for HIPAA-covered transactions
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- Block
- D55-D59 Hemolytic anemias
- Parent codes
- D56
Notes inherited from parent codes
Instructional notes at a category or block level apply to every code below it.
D56 – Thalassemia
Excludes1 (not coded here):
- sickle-cell thalassemia (D57.4-)
Index terms for D56.4
Entries in the ICD-10-CM alphabetic index that lead to this code:
Related codes in D56
- D56.0 – Alpha thalassemiaBillable
- D56.1 – Beta thalassemiaBillable
- D56.2 – Delta-beta thalassemiaBillable
- D56.3 – Thalassemia minorBillable
- D56.5 – Hemoglobin E-beta thalassemiaBillable
- D56.8 – Other thalassemiasBillable
- D56.9 – Thalassemia, unspecifiedBillable
Frequently asked questions
What is ICD-10 code D56.4?
D56.4 is the ICD-10-CM code for hereditary persistence of fetal hemoglobin [HPFH], in the block D55-D59 (Hemolytic anemias).
Is D56.4 a billable code?
Yes. D56.4 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.
What category does D56.4 belong to?
It belongs to category D56 – Thalassemia.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.