C96.5 – Multifocal and unisystemic Langerhans-cell histiocytosis

ICD-10-CM 2027 diagnosis code · Malignant neoplasms of lymphoid, hematopoietic and related tissue

Billable code

ICD-10-CM code C96.5
Code
C96.5 (claims format: C965)
Description
Multifocal and unisystemic Langerhans-cell histiocytosis
Billable
Yes – valid for HIPAA-covered transactions
Valid for
Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter
2. Neoplasms (C00-D49)
Block
C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue
Parent codes
C96

Notes for C96.5

Applicable to:
  • Hand-Schüller-Christian disease
  • Histiocytosis X, multifocal
Excludes1 (not coded here):
  • multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0)
  • unifocal Langerhans-cell histiocytosis (C96.6)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

C96 – Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue

Excludes1 (not coded here):
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Block C81-C96

Excludes2 (not included here):
  • Kaposi's sarcoma of lymph nodes (C46.3)
  • secondary and unspecified neoplasm of lymph nodes (C77.-)
  • secondary neoplasm of bone marrow (C79.52)
  • secondary neoplasm of spleen (C78.89)

Index terms for C96.5

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in C96

Frequently asked questions

What is ICD-10 code C96.5?

C96.5 is the ICD-10-CM code for multifocal and unisystemic Langerhans-cell histiocytosis, in the block C81-C96 (Malignant neoplasms of lymphoid, hematopoietic and related tissue).

Is C96.5 a billable code?

Yes. C96.5 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does C96.5 belong to?

It belongs to category C96 – Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.