ICD-10 Code for Dependence

The default ICD-10-CM 2027 code for dependence (on) (syndrome) is F19.20 – Other psychoactive substance dependence, uncomplicated. More specific codes depend on the details documented, as listed in the official index (185 codes, 185 billable).

Main code: F19.20 – Other psychoactive substance dependence, uncomplicated
Billable: Yes

Index entries for Dependence

with remission – F19.21
alcohol (ethyl) (methyl) (without remission) – F10.20
- with
  - amnestic disorder, persisting – F10.26
  - anxiety disorder – F10.280
  - dementia, persisting – F10.27
  - intoxication – F10.229
    - with delirium – F10.221
    - uncomplicated – F10.220
  - mood disorder – F10.24
  - psychotic disorder – F10.259
    - with
      - delusions – F10.250
      - hallucinations – F10.251
  - remission – F10.21
  - sexual dysfunction – F10.281
  - sleep disorder – F10.282
  - specified disorder NEC – F10.288
  - withdrawal – F10.239
    - with
      - delirium – F10.231
      - perceptual disturbance – F10.232
    - uncomplicated – F10.230
- counseling and surveillance – Z71.41
- in remission – F10.21
amobarbital – see Dependence, drug, sedative
amphetamine (s) (type) – see Dependence, drug, stimulant NEC
amytal (sodium) – see Dependence, drug, sedative
analgesic NEC – F55.8
anesthetic (agent) (gas) (general) (local) – see Dependence, drug, psychoactive NEC
anxiolytic NEC – see Dependence, drug, sedative
barbital (s) – see Dependence, drug, sedative
barbiturate (s) (compounds) (drugs classifiable to T42) – see Dependence, drug, sedative
benzedrine – see Dependence, drug, stimulant NEC
bhang – see Dependence, drug, cannabis
bromide (s) – see Dependence, drug, sedative
caffeine – see Dependence, drug, stimulant NEC
cannabis (sativa) (indica) (resin) (derivatives) (type) – see Dependence, drug, cannabis
chloral (betaine) (hydrate) – see Dependence, drug, sedative
chlordiazepoxide – see Dependence, drug, sedative
coca (leaf) (derivatives) – see Dependence, drug, cocaine
cocaine – see Dependence, drug, cocaine
codeine – see Dependence, drug, opioid
combinations of drugs – F19.20
dagga – see Dependence, drug, cannabis
demerol – see Dependence, drug, opioid
dexamphetamine – see Dependence, drug, stimulant NEC
dexedrine – see Dependence, drug, stimulant NEC
dextromethorphan – see Dependence, drug, opioid
dextromoramide – see Dependence, drug, opioid
dextro-nor-pseudo-ephedrine – see Dependence, drug, stimulant NEC
dextrorphan – see Dependence, drug, opioid
diazepam – see Dependence, drug, sedative
dilaudid – see Dependence, drug, opioid
D-lysergic acid diethylamide – see Dependence, drug, hallucinogen
drug NEC – F19.20
- with sleep disorder – F19.282
- cannabis – F12.20
  - with
    - anxiety disorder – F12.280
    - intoxication – F12.229
      - with
        delirium – F12.221
        perceptual disturbance – F12.222
      - uncomplicated – F12.220
    - other specified disorder – F12.288
    - psychosis – F12.259
      - delusions – F12.250
      - hallucinations – F12.251
    - unspecified disorder – F12.29
    - withdrawal – F12.23
  - in remission – F12.21
- cocaine – F14.20
  - with
    - anxiety disorder – F14.280
    - intoxication – F14.229
      - with
        delirium – F14.221
        perceptual disturbance – F14.222
      - uncomplicated – F14.220
    - mood disorder – F14.24
    - other specified disorder – F14.288
    - psychosis – F14.259
      - delusions – F14.250
      - hallucinations – F14.251
    - sexual dysfunction – F14.281
    - sleep disorder – F14.282
    - unspecified disorder – F14.29
    - withdrawal – F14.23
  - in remission – F14.21
  - withdrawal symptoms in newborn – P96.1
- counseling and surveillance – Z71.51
- hallucinogen – F16.20
  - with
    - anxiety disorder – F16.280
    - flashbacks – F16.283
    - intoxication – F16.229
      - with delirium – F16.221
      - uncomplicated – F16.220
    - mood disorder – F16.24
    - other specified disorder – F16.288
    - perception disorder, persisting – F16.283
    - psychosis – F16.259
      - delusions – F16.250
      - hallucinations – F16.251
    - unspecified disorder – F16.29
  - in remission – F16.21
- in remission – F19.21
- inhalant – F18.20
  - with
    - anxiety disorder – F18.280
    - dementia, persisting – F18.27
    - intoxication – F18.229
      - with delirium – F18.221
      - uncomplicated – F18.220
    - mood disorder – F18.24
    - other specified disorder – F18.288
    - psychosis – F18.259
      - delusions – F18.250
      - hallucinations – F18.251
    - unspecified disorder – F18.29
  - in remission – F18.21
- nicotine – F17.200
  - with disorder – F17.209
    - in remission – F17.201
    - specified disorder NEC – F17.208
    - withdrawal – F17.203
  - chewing tobacco – F17.220
    - with disorder – F17.229
      - in remission – F17.221
      - specified disorder NEC – F17.228
      - withdrawal – F17.223
  - cigarettes – F17.210
    - with disorder – F17.219
      - in remission – F17.211
      - specified disorder NEC – F17.218
      - withdrawal – F17.213
  - specified product NEC – F17.290
    - with disorder – F17.299
      - remission – F17.291
      - specified disorder NEC – F17.298
      - withdrawal – F17.293
- opioid – F11.20
  - with
    - intoxication – F11.229
      - with
        delirium – F11.221
        perceptual disturbance – F11.222
      - uncomplicated – F11.220
    - mood disorder – F11.24
    - opioid-associated amnestic syndrome – F11.288
    - other specified disorder – F11.288
    - psychosis – F11.259
      - delusions – F11.250
      - hallucinations – F11.251
    - sexual dysfunction – F11.281
    - sleep disorder – F11.282
    - unspecified disorder – F11.29
    - withdrawal – F11.23
  - in remission – F11.21
- psychoactive NEC – F19.20
  - with
    - amnestic disorder – F19.26
    - anxiety disorder – F19.280
    - dementia – F19.27
    - intoxication – F19.229
      - with
        delirium – F19.221
        perceptual disturbance – F19.222
      - uncomplicated – F19.220
    - mood disorder – F19.24
    - other specified disorder – F19.288
    - psychosis – F19.259
      - delusions – F19.250
      - hallucinations – F19.251
    - sexual dysfunction – F19.281
    - sleep disorder – F19.282
    - unspecified disorder – F19.29
    - withdrawal – F19.239
      - with
        delirium – F19.231
        perceptual disturbance – F19.232
      - uncomplicated – F19.230
  - in remission – F19.21
- sedative, hypnotic or anxiolytic – F13.20
  - with
    - amnestic disorder – F13.26
    - anxiety disorder – F13.280
    - dementia, persisting – F13.27
    - intoxication – F13.229
      - with delirium – F13.221
      - uncomplicated – F13.220
    - mood disorder – F13.24
    - other specified disorder – F13.288
    - psychosis – F13.259
      - delusions – F13.250
      - hallucinations – F13.251
    - sexual dysfunction – F13.281
    - sleep disorder – F13.282
    - unspecified disorder – F13.29
    - withdrawal – F13.239
      - with
        delirium – F13.231
        perceptual disturbance – F13.232
      - uncomplicated – F13.230
  - in remission – F13.21
- stimulant NEC – F15.20
  - with
    - anxiety disorder – F15.280
    - intoxication – F15.229
      - with
        delirium – F15.221
        perceptual disturbance – F15.222
      - uncomplicated – F15.220
    - mood disorder – F15.24
    - other specified disorder – F15.288
    - psychosis – F15.259
      - delusions – F15.250
      - hallucinations – F15.251
    - sexual dysfunction – F15.281
    - sleep disorder – F15.282
    - unspecified disorder – F15.29
    - withdrawal – F15.23
  - in remission – F15.21
ethyl
- alcohol (without remission) – F10.20
  - with remission – F10.21
- bromide – see Dependence, drug, sedative
- carbamate – F19.20
- chloride – F19.20
- morphine – see Dependence, drug, opioid
ganja – see Dependence, drug, cannabis
glue (airplane) (sniffing) – see Dependence, drug, inhalant
glutethimide – see Dependence, drug, sedative
hallucinogenics – see Dependence, drug, hallucinogen
hashish – see Dependence, drug, cannabis
hemp – see Dependence, drug, cannabis
heroin (salt) (any) – see Dependence, drug, opioid
hypnotic NEC – see Dependence, drug, sedative
Indian hemp – see Dependence, drug, cannabis
inhalants – see Dependence, drug, inhalant
khat – see Dependence, drug, stimulant NEC
laudanum – see Dependence, drug, opioid
LSD (-25) (derivatives) – see Dependence, drug, hallucinogen
luminal – see Dependence, drug, sedative
lysergic acid – see Dependence, drug, hallucinogen
maconha – see Dependence, drug, cannabis
marihuana – see Dependence, drug, cannabis
meprobamate – see Dependence, drug, sedative
mescaline – see Dependence, drug, hallucinogen
methadone – see Dependence, drug, opioid
methamphetamine (s) – see Dependence, drug, stimulant NEC
methaqualone – see Dependence, drug, sedative
methyl
- alcohol (without remission) – F10.20
  - with remission – F10.21
- bromide – see Dependence, drug, sedative
- morphine – see Dependence, drug, opioid
- phenidate – see Dependence, drug, stimulant NEC
- sulfonal – see Dependence, drug, sedative
morphine (sulfate) (sulfite) (type) – see Dependence, drug, opioid
narcotic (drug) – see Dependence, drug, opioid
nembutal – see Dependence, drug, sedative
neraval – see Dependence, drug, sedative
neravan – see Dependence, drug, sedative
neurobarb – see Dependence, drug, sedative
nicotine – see Dependence, drug, nicotine
nitrous oxide – F19.20
nonbarbiturate sedatives and tranquilizers with similar effect – see Dependence, drug, sedative
on
- artificial heart (fully implantable) (mechanical) – Z95.812
- aspirator – Z99.0
- care provider (because of) – Z74.9
  - impaired mobility – Z74.09
  - need for
    - assistance with personal care – Z74.1
    - continuous supervision – Z74.3
  - no other household member able to render care – Z74.2
  - specified reason NEC – Z74.8
- machine – Z99.89
  - enabling NEC – Z99.89
  - specified type NEC – Z99.89
- renal dialysis (hemodialysis) (peritoneal) – Z99.2
- respirator – Z99.11
- ventilator – Z99.11
- wheelchair – Z99.3
opiate – see Dependence, drug, opioid
opioids – see Dependence, drug, opioid
opium (alkaloids) (derivatives) (tincture) – see Dependence, drug, opioid
oxygen (long-term) (supplemental) – Z99.81
paraldehyde – see Dependence, drug, sedative
paregoric – see Dependence, drug, opioid
PCP (phencyclidine) (or related substance) – see Dependence, drug, hallucinogen
pentobarbital – see Dependence, drug, sedative
pentobarbitone (sodium) – see Dependence, drug, sedative
pentothal – see Dependence, drug, sedative
peyote – see Dependence, drug, hallucinogen
phencyclidine (PCP) (or related substance) – see Dependence, drug, hallucinogen
phenmetrazine – see Dependence, drug, stimulant NEC
phenobarbital – see Dependence, drug, sedative
polysubstance – F19.20
psilocibin, psilocin, psilocyn, psilocyline – see Dependence, drug, hallucinogen
psychostimulant NEC – see Dependence, drug, stimulant NEC
secobarbital – see Dependence, drug, sedative
seconal – see Dependence, drug, sedative
sedative NEC – see Dependence, drug, sedative
specified drug NEC – see Dependence, drug
stimulant NEC – see Dependence, drug, stimulant NEC
substance NEC – see Dependence, drug
supplemental oxygen – Z99.81
tobacco – see Dependence, drug, nicotine
- counseling and surveillance – Z71.6
tranquilizer NEC – see Dependence, drug, sedative
vitamin B6 – E53.1
volatile solvents – see Dependence, drug, inhalant

How to choose the right code

Start with the main term, then pick the indented subterm that matches the documentation (type, cause, site, laterality, episode of care). Always confirm the code in the tabular list: follow its Excludes1/Excludes2, “code first” and “use additional code” notes, and add a 7th character where required.

Source: CDC/NCHS ICD-10-CM FY2027 alphabetic index.