C5271 – Application of low cost skin substitute graft to trunk, arms, legs, total wound surface area up to 100 sq cm; first 25 sq cm or less wound surface area

HCPCS Level II code · C codes: Outpatient PPS (Hospital Outpatient)

Discontinued December 31, 2025 Special coverage instructions apply

HCPCS codeC5271
Long description
Application of low cost skin substitute graft to trunk, arms, legs, total wound surface area up to 100 sq cm; first 25 sq cm or less wound surface area
Short description
Low cost skin substitute app
Pricing indicator
53 Statute
Medicare coverage
D Special coverage instructions apply
BETOS category
P5A Ambulatory procedures - skin
Added
January 1, 2014
Last change
January 1, 2026 – No change
Termination date
December 31, 2025

Frequently asked questions

What is HCPCS code C5271?

C5271 is a HCPCS Level II code for application of low cost skin substitute graft to trunk, arms, legs, total wound surface area up to 100 sq cm; first 25 sq cm or less wound surface area. It was discontinued on December 31, 2025.

Does Medicare cover C5271?

The HCPCS file lists coverage code D: Special coverage instructions apply. Coverage and payment also depend on local coverage determinations and the patient’s plan.

Nearby C codes

Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.