Z79.81 – Long term (current) use of agents affecting estrogen receptors and estrogen levels

ICD-10-CM 2027 diagnosis code · Persons with potential health hazards related to family and personal history and certain conditions influencing health status

Non-billable header

ICD-10-CM code Z79.81
Code
Z79.81 (claims format: Z7981)
Description
Long term (current) use of agents affecting estrogen receptors and estrogen levels
Short description
Lng trm (crnt) use of agnt aff estrog recpt & estrog levels
Billable
No – use a more specific code below
Valid for
Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter
21. Factors influencing health status and contact with health services (Z00-Z99)
Block
Z77-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
Parent codes
Z79 › Z79.8

Billable codes under Z79.81

Z79.81 is a header code and cannot be used on claims. Choose the most specific code:

Notes for Z79.81

Excludes1 (not coded here):
  • hormone replacement therapy (Z79.890)
Code first:
  • , if applicable:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of prostate (C61)
Use additional code:
  • code, if applicable, to identify:
  • estrogen receptor positive status (Z17.0)
  • family history of breast cancer (Z80.3)
  • genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
  • personal history of breast cancer (Z85.3)
  • personal history of prostate cancer (Z85.46)
  • postmenopausal status (Z78.0)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Z79 – Long term (current) drug therapy

Includes:
  • long term (current) drug use for prophylactic purposes
Excludes2 (not included here):
  • drug abuse and dependence (F11-F19)
  • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
Code also:
  • any therapeutic drug level monitoring (Z51.81)

Block Z77-Z99

Code also:
  • any follow-up examination (Z08-Z09)

Related codes in Z79.8

Frequently asked questions

What is ICD-10 code Z79.81?

Z79.81 is the ICD-10-CM code for long term (current) use of agents affecting estrogen receptors and estrogen levels, in the block Z77-Z99 (Persons with potential health hazards related to family and personal history and certain conditions influencing health status).

Is Z79.81 a billable code?

No. Z79.81 is a header code with more specific child codes; report one of the billable codes listed above.

What category does Z79.81 belong to?

It belongs to category Z79 – Long term (current) drug therapy.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.