R53.81 – Other malaise

ICD-10-CM 2027 diagnosis code · General symptoms and signs

Billable code

ICD-10-CM code R53.81

Code: R53.81 (claims format: R5381)
Description: Other malaise
Billable: Yes – valid for HIPAA-covered transactions
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 18. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Block: R50-R69 General symptoms and signs
Parent codes: R53 › R53.8

Notes for R53.81

Applicable to:

Chronic debility
Debility NOS
General physical deterioration
Malaise NOS
Nervous debility

Excludes1 (not coded here):

age-related physical debility (R54)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

R53.8 – Other malaise and fatigue

Excludes1 (not coded here):

combat exhaustion and fatigue (F43.0)
congenital debility (P96.9)
exhaustion and fatigue due to excessive exertion (T73.3)
exhaustion and fatigue due to exposure (T73.2)
exhaustion and fatigue due to heat (T67.-)
exhaustion and fatigue due to pregnancy (O26.8-)
exhaustion and fatigue due to recurrent depressive episode (F33-)
exhaustion and fatigue due to senile debility (R54)

Index terms for R53.81

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in R53.8

R53.82 – Chronic fatigue, unspecifiedBillable
R53.83 – Other fatigueBillable

Frequently asked questions

What is ICD-10 code R53.81?

R53.81 is the ICD-10-CM code for other malaise, in the block R50-R69 (General symptoms and signs).

Is R53.81 a billable code?

Yes. R53.81 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does R53.81 belong to?

It belongs to category R53 – Malaise and fatigue.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.