E22.8 – Other hyperfunction of pituitary gland

ICD-10-CM 2027 diagnosis code · Disorders of other endocrine glands

Billable code

ICD-10-CM code E22.8

Code: E22.8 (claims format: E228)
Description: Other hyperfunction of pituitary gland
Billable: Yes – valid for HIPAA-covered transactions
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 4. Endocrine, nutritional and metabolic diseases (E00-E89)
Block: E20-E35 Disorders of other endocrine glands
Parent codes: E22

Notes for E22.8

Applicable to:

Central precocious puberty

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

E22 – Hyperfunction of pituitary gland

Excludes1 (not coded here):

Cushing's syndrome (E24.-)
Nelson's syndrome (E24.1)
overproduction of ACTH not associated with Cushing's disease (E27.0)
overproduction of pituitary ACTH (E24.0)
overproduction of thyroid-stimulating hormone (E05.8-)

Block E20-E35

Excludes1 (not coded here):

galactorrhea (N64.3)
gynecomastia (N62)

Index terms for E22.8

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in E22

E22.0 – Acromegaly and pituitary gigantismBillable
E22.1 – HyperprolactinemiaBillable
E22.2 – Syndrome of inappropriate secretion of antidiuretic hormoneBillable
E22.9 – Hyperfunction of pituitary gland, unspecifiedBillable

Frequently asked questions

What is ICD-10 code E22.8?

E22.8 is the ICD-10-CM code for other hyperfunction of pituitary gland, in the block E20-E35 (Disorders of other endocrine glands).

Is E22.8 a billable code?

Yes. E22.8 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does E22.8 belong to?

It belongs to category E22 – Hyperfunction of pituitary gland.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.