E08.21 – Diabetes mellitus due to underlying condition with diabetic nephropathy

ICD-10-CM 2027 diagnosis code · Diabetes mellitus

Billable code

ICD-10-CM code E08.21
Code
E08.21 (claims format: E0821)
Description
Diabetes mellitus due to underlying condition with diabetic nephropathy
Short description
Diabetes due to underlying condition w diabetic nephropathy
Billable
Yes – valid for HIPAA-covered transactions
Valid for
Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter
4. Endocrine, nutritional and metabolic diseases (E00-E89)
Block
E08-E13 Diabetes mellitus
Parent codes
E08 › E08.2

Notes for E08.21

Applicable to:
  • Diabetes mellitus due to underlying condition with intercapillary glomerulosclerosis
  • Diabetes mellitus due to underlying condition with intracapillary glomerulonephrosis
  • Diabetes mellitus due to underlying condition with Kimmelstiel-Wilson disease

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

E08 – Diabetes mellitus due to underlying condition

Excludes1 (not coded here):
  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 1 diabetes mellitus (E10.-)
  • type 2 diabetes mellitus (E11.-)
Code first:
  • the underlying condition, such as:
  • congenital rubella (P35.0)
  • Cushing's syndrome (E24.-)
  • cystic fibrosis (E84.-)
  • malignant neoplasm (C00-C96)
  • malnutrition (E40-E46)
  • pancreatitis and other diseases of the pancreas (K85-K86.-)
Use additional code:
  • code to identify control using:
  • injectable non-insulin antidiabetic drugs (Z79.85)
  • insulin (Z79.4)
  • oral antidiabetic drugs (Z79.84)
  • oral hypoglycemic drugs (Z79.84)

Index terms for E08.21

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in E08.2

Frequently asked questions

What is ICD-10 code E08.21?

E08.21 is the ICD-10-CM code for diabetes mellitus due to underlying condition with diabetic nephropathy, in the block E08-E13 (Diabetes mellitus).

Is E08.21 a billable code?

Yes. E08.21 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does E08.21 belong to?

It belongs to category E08 – Diabetes mellitus due to underlying condition.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.