D75.81 – Myelofibrosis

ICD-10-CM 2027 diagnosis code · Other disorders of blood and blood-forming organs

Billable code

ICD-10-CM code D75.81
Code
D75.81 (claims format: D7581)
Description
Myelofibrosis
Billable
Yes – valid for HIPAA-covered transactions
Valid for
Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter
3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Block
D70-D77 Other disorders of blood and blood-forming organs
Parent codes
D75 › D75.8

Notes for D75.81

Applicable to:
  • Myelofibrosis NOS
  • Secondary myelofibrosis NOS
Excludes1 (not coded here):
  • acute myelofibrosis (C94.4-)
  • idiopathic myelofibrosis (D47.1)
  • leukoerythroblastic anemia (D61.82)
  • myelofibrosis with myeloid metaplasia (D47.4)
  • myelophthisic anemia (D61.82)
  • myelophthisis (D61.82)
  • primary myelofibrosis (D47.1)
Code first:
  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)
Use additional code:
  • code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)
  • code for adverse effect, if applicable, to identify drug (T45.1X5)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

D75 – Other and unspecified diseases of blood and blood-forming organs

Excludes2 (not included here):
  • acute lymphadenitis (L04.-)
  • chronic lymphadenitis (I88.1)
  • enlarged lymph nodes (R59.-)
  • hypergammaglobulinemia NOS (D89.2)
  • lymphadenitis NOS (I88.9)
  • mesenteric lymphadenitis (acute) (chronic) (I88.0)

Index terms for D75.81

Entries in the ICD-10-CM alphabetic index that lead to this code:

Related codes in D75.8

Frequently asked questions

What is ICD-10 code D75.81?

D75.81 is the ICD-10-CM code for myelofibrosis, in the block D70-D77 (Other disorders of blood and blood-forming organs).

Is D75.81 a billable code?

Yes. D75.81 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.

What category does D75.81 belong to?

It belongs to category D75 – Other and unspecified diseases of blood and blood-forming organs.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.