D61.81 – Pancytopenia

ICD-10-CM 2027 diagnosis code · Aplastic and other anemias and other bone marrow failure syndromes

Non-billable header

ICD-10-CM code D61.81

Code: D61.81 (claims format: D6181)
Description: Pancytopenia
Billable: No – use a more specific code below
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 3. Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Block: D60-D64 Aplastic and other anemias and other bone marrow failure syndromes
Parent codes: D61 › D61.8

Billable codes under D61.81

D61.81 is a header code and cannot be used on claims. Choose the most specific code:

D61.810 – Antineoplastic chemotherapy induced pancytopeniaBillable
D61.811 – Other drug-induced pancytopeniaBillable
D61.818 – Other pancytopeniaBillable

Notes for D61.81

Excludes1 (not coded here):

pancytopenia (due to) (with) aplastic anemia (D61.9)
pancytopenia (due to) (with) bone marrow infiltration (D61.82)
pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
pancytopenia (due to) (with) myeloproliferative disease (D47.1)

Excludes2 (not included here):

pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

D61 – Other aplastic anemias and other bone marrow failure syndromes

Excludes2 (not included here):

neutropenia (D70.-)

Related codes in D61.8

Frequently asked questions

What is ICD-10 code D61.81?

D61.81 is the ICD-10-CM code for pancytopenia, in the block D60-D64 (Aplastic and other anemias and other bone marrow failure syndromes).

Is D61.81 a billable code?

No. D61.81 is a header code with more specific child codes; report one of the billable codes listed above.

What category does D61.81 belong to?

It belongs to category D61 – Other aplastic anemias and other bone marrow failure syndromes.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.