D21 – Other benign neoplasms of connective and other soft tissue
ICD-10-CM 2027 diagnosis code · Benign neoplasms, except benign neuroendocrine tumors
ICD-10-CM code
D21
- Code
D21(claims format:D21)- Description
- Other benign neoplasms of connective and other soft tissue
- Billable
- No – use a more specific code below
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 2. Neoplasms (C00-D49)
- Block
- D10-D36 Benign neoplasms, except benign neuroendocrine tumors
Billable codes under D21
D21 is a header code and cannot be used on claims. Choose the most specific code:
- D21.0 – Benign neoplasm of connective and other soft tissue of head, face and neckBillable
- D21.1 – Benign neoplasm of connective and other soft tissue of upper limb, including shoulderHeader (more codes below)
- D21.2 – Benign neoplasm of connective and other soft tissue of lower limb, including hipHeader (more codes below)
- D21.3 – Benign neoplasm of connective and other soft tissue of thoraxBillable
- D21.4 – Benign neoplasm of connective and other soft tissue of abdomenBillable
- D21.5 – Benign neoplasm of connective and other soft tissue of pelvisBillable
- D21.6 – Benign neoplasm of connective and other soft tissue of trunk, unspecifiedBillable
- D21.9 – Benign neoplasm of connective and other soft tissue, unspecifiedBillable
Notes for D21
Includes:
- benign neoplasm of blood vessel
- benign neoplasm of bursa
- benign neoplasm of cartilage
- benign neoplasm of fascia
- benign neoplasm of fat
- benign neoplasm of ligament, except uterine
- benign neoplasm of lymphatic channel
- benign neoplasm of muscle
- benign neoplasm of synovia
- benign neoplasm of tendon (sheath)
- benign stromal tumors
Excludes1 (not coded here):
- benign neoplasm of articular cartilage (D16.-)
- benign neoplasm of cartilage of larynx (D14.1)
- benign neoplasm of cartilage of nose (D14.0)
- benign neoplasm of connective tissue of breast (D24.-)
- benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
- benign neoplasm of peritoneum (D20.1)
- benign neoplasm of retroperitoneum (D20.0)
- benign neoplasm of uterine ligament, any (D28.2)
- benign neoplasm of vascular tissue (D18.-)
- hemangioma (D18.0-)
- lipomatous neoplasm (D17.-)
- lymphangioma (D18.1)
- uterine leiomyoma (D25.-)
Frequently asked questions
What is ICD-10 code D21?
D21 is the ICD-10-CM code for other benign neoplasms of connective and other soft tissue, in the block D10-D36 (Benign neoplasms, except benign neuroendocrine tumors).
Is D21 a billable code?
No. D21 is a header code with more specific child codes; report one of the billable codes listed above.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.