C25.4 – Malignant neoplasm of endocrine pancreas
ICD-10-CM 2027 diagnosis code · Malignant neoplasms of digestive organs
ICD-10-CM code
C25.4
- Code
C25.4(claims format:C254)- Description
- Malignant neoplasm of endocrine pancreas
- Billable
- Yes – valid for HIPAA-covered transactions
- Valid for
- Dates of service October 1, 2026 – September 30, 2027 (FY2027)
- Chapter
- 2. Neoplasms (C00-D49)
- Block
- C15-C26 Malignant neoplasms of digestive organs
- Parent codes
- C25
Notes for C25.4
Applicable to:
- Malignant neoplasm of islets of Langerhans
Use additional code:
- code to identify any functional activity.
Notes inherited from parent codes
Instructional notes at a category or block level apply to every code below it.
C25 – Malignant neoplasm of pancreas
Use additional code:
- code to identify:
- alcohol abuse and dependence (F10.-)
Code also:
- if applicable exocrine pancreatic insufficiency (K86.81)
Block C15-C26
Excludes1 (not coded here):
- Kaposi's sarcoma of gastrointestinal sites (C46.4)
Excludes2 (not included here):
- gastrointestinal stromal tumors (C49.A-)
Index terms for C25.4
Entries in the ICD-10-CM alphabetic index that lead to this code:
- Carcinoma, islet cell, pancreas
- Gastrinoma, malignant, pancreas
- Insulinoma, pancreas, malignant
- Glucagonoma, pancreas, malignant
- Tumor, G cell, malignant, pancreas
- Adenocarcinoma, islet cell, pancreas
- Tumor, beta-cell, malignant, pancreas
- Tumor, alpha-cell, malignant, pancreas
- Tumor, islet cell, malignant, pancreas
- Carcinoma, islet cell, unspecified site
- Gastrinoma, malignant, unspecified site
- Insulinoma, unspecified site, malignant
- Glucagonoma, unspecified site, malignant
- Tumor, G cell, malignant, unspecified site
- Adenocarcinoma, islet cell, unspecified site
- Tumor, beta-cell, malignant, unspecified site
- Tumor, alpha-cell, malignant, unspecified site
- Tumor, islet cell, malignant, unspecified site
Related codes in C25
- C25.0 – Malignant neoplasm of head of pancreasBillable
- C25.1 – Malignant neoplasm of body of pancreasBillable
- C25.2 – Malignant neoplasm of tail of pancreasBillable
- C25.3 – Malignant neoplasm of pancreatic ductBillable
- C25.7 – Malignant neoplasm of other parts of pancreasBillable
- C25.8 – Malignant neoplasm of overlapping sites of pancreasBillable
- C25.9 – Malignant neoplasm of pancreas, unspecifiedBillable
Frequently asked questions
What is ICD-10 code C25.4?
C25.4 is the ICD-10-CM code for malignant neoplasm of endocrine pancreas, in the block C15-C26 (Malignant neoplasms of digestive organs).
Is C25.4 a billable code?
Yes. C25.4 is a billable/specific code that can be used to indicate a diagnosis for reimbursement purposes.
What category does C25.4 belong to?
It belongs to category C25 – Malignant neoplasm of pancreas.
Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.