C22 – Malignant neoplasm of liver and intrahepatic bile ducts

ICD-10-CM 2027 diagnosis code · Malignant neoplasms of digestive organs

Non-billable header

ICD-10-CM code C22

Code: C22 (claims format: C22)
Description: Malignant neoplasm of liver and intrahepatic bile ducts
Billable: No – use a more specific code below
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 2. Neoplasms (C00-D49)
Block: C15-C26 Malignant neoplasms of digestive organs

Billable codes under C22

C22 is a header code and cannot be used on claims. Choose the most specific code:

C22.0 – Liver cell carcinomaBillable
C22.1 – Intrahepatic bile duct carcinomaBillable
C22.2 – HepatoblastomaBillable
C22.3 – Angiosarcoma of liverBillable
C22.4 – Other sarcomas of liverBillable
C22.7 – Other specified carcinomas of liverBillable
C22.8 – Malignant neoplasm of liver, primary, unspecified as to typeBillable
C22.9 – Malignant neoplasm of liver, not specified as primary or secondaryBillable

Notes for C22

Excludes1 (not coded here):

malignant neoplasm of biliary tract NOS (C24.9)
secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)

Use additional code:

code to identify:
alcohol abuse and dependence (F10.-)
hepatitis B (B16.-, B18.0-B18.1)
hepatitis C (B17.1-, B18.2)

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Block C15-C26

Excludes1 (not coded here):

Kaposi's sarcoma of gastrointestinal sites (C46.4)

Excludes2 (not included here):

gastrointestinal stromal tumors (C49.A-)

Frequently asked questions

What is ICD-10 code C22?

C22 is the ICD-10-CM code for malignant neoplasm of liver and intrahepatic bile ducts, in the block C15-C26 (Malignant neoplasms of digestive organs).

Is C22 a billable code?

No. C22 is a header code with more specific child codes; report one of the billable codes listed above.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.