A53 – Other and unspecified syphilis

ICD-10-CM 2027 diagnosis code · Infections with a predominantly sexual mode of transmission

Non-billable header

ICD-10-CM code A53
Code
A53 (claims format: A53)
Description
Other and unspecified syphilis
Billable
No – use a more specific code below
Valid for
Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter
1. Certain infectious and parasitic diseases (A00-B99)
Block
A50-A64 Infections with a predominantly sexual mode of transmission

Billable codes under A53

A53 is a header code and cannot be used on claims. Choose the most specific code:

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Block A50-A64

Excludes1 (not coded here):
  • nonspecific and nongonococcal urethritis (N34.1)
  • Reiter's disease (M02.3-)
Excludes2 (not included here):
  • human immunodeficiency virus [HIV] disease (B20)

Frequently asked questions

What is ICD-10 code A53?

A53 is the ICD-10-CM code for other and unspecified syphilis, in the block A50-A64 (Infections with a predominantly sexual mode of transmission).

Is A53 a billable code?

No. A53 is a header code with more specific child codes; report one of the billable codes listed above.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.