A52.1 – Symptomatic neurosyphilis

ICD-10-CM 2027 diagnosis code · Infections with a predominantly sexual mode of transmission

Non-billable header

ICD-10-CM code A52.1

Code: A52.1 (claims format: A521)
Description: Symptomatic neurosyphilis
Billable: No – use a more specific code below
Valid for: Dates of service October 1, 2026 – September 30, 2027 (FY2027)
Chapter: 1. Certain infectious and parasitic diseases (A00-B99)
Block: A50-A64 Infections with a predominantly sexual mode of transmission
Parent codes: A52

Billable codes under A52.1

A52.1 is a header code and cannot be used on claims. Choose the most specific code:

A52.10 – Symptomatic neurosyphilis, unspecifiedBillable
A52.11 – Tabes dorsalisBillable
A52.12 – Other cerebrospinal syphilisBillable
A52.13 – Late syphilitic meningitisBillable
A52.14 – Late syphilitic encephalitisBillable
A52.15 – Late syphilitic neuropathyBillable
A52.16 – Charcot's arthropathy (tabetic)Billable
A52.17 – General paresisBillable
A52.19 – Other symptomatic neurosyphilisBillable

Notes inherited from parent codes

Instructional notes at a category or block level apply to every code below it.

Block A50-A64

Excludes1 (not coded here):

nonspecific and nongonococcal urethritis (N34.1)
Reiter's disease (M02.3-)

Excludes2 (not included here):

human immunodeficiency virus [HIV] disease (B20)

Related codes in A52

A52.0 – Cardiovascular and cerebrovascular syphilisHeader
A52.2 – Asymptomatic neurosyphilisBillable
A52.3 – Neurosyphilis, unspecifiedBillable
A52.7 – Other symptomatic late syphilisHeader
A52.8 – Late syphilis, latentBillable
A52.9 – Late syphilis, unspecifiedBillable

Frequently asked questions

What is ICD-10 code A52.1?

A52.1 is the ICD-10-CM code for symptomatic neurosyphilis, in the block A50-A64 (Infections with a predominantly sexual mode of transmission).

Is A52.1 a billable code?

No. A52.1 is a header code with more specific child codes; report one of the billable codes listed above.

What category does A52.1 belong to?

It belongs to category A52 – Late syphilis.

Source: CDC/NCHS ICD-10-CM FY2027 code files, tabular list and index. Reference only – code assignment must follow the official ICD-10-CM guidelines and documentation in the medical record.