ICD-10 Code for Tumor Lysis Syndrome

The default ICD-10-CM 2027 code for tumor lysis syndrome (following antineoplastic chemotherapy) (spontaneous) is E88.3 – Tumor lysis syndrome. More specific codes depend on the details documented, as listed in the official index (1 codes, 1 billable).

Main code
E88.3 – Tumor lysis syndrome
Billable
Yes

How to choose the right code

Start with the main term, then pick the indented subterm that matches the documentation (type, cause, site, laterality, episode of care). Always confirm the code in the tabular list: follow its Excludes1/Excludes2, “code first” and “use additional code” notes, and add a 7th character where required.

Source: CDC/NCHS ICD-10-CM FY2027 alphabetic index.