ICD-10 Code for Amyloidosis

The default ICD-10-CM 2027 code for amyloidosis (generalized) (primary) is E85.9 – Amyloidosis, unspecified. More specific codes depend on the details documented, as listed in the official index (13 codes, 13 billable).

Main code: E85.9 – Amyloidosis, unspecified
Billable: Yes

Index entries for Amyloidosis

with lung involvement – E85.4 – J99 [manifestation]
familial – E85.2
genetic – E85.2
heart – E85.4 – I43 [manifestation]
hemodialysis-associated – E85.3
light chain (AL) – E85.81
liver – E85.4 – K77 [manifestation]
localized – E85.4
neuropathic heredofamilial – E85.1
non-neuropathic heredofamilial – E85.0
organ limited – E85.4
Portuguese – E85.1
pulmonary – E85.4 – J99 [manifestation]
secondary systemic – E85.3
senile systemic (SSA) – E85.82
skin (lichen) (macular) – E85.4 – L99 [manifestation]
specified NEC – E85.89
subglottic – E85.4 – J99 [manifestation]
wild-type transthyretin-related (ATTR) – E85.82

How to choose the right code

Start with the main term, then pick the indented subterm that matches the documentation (type, cause, site, laterality, episode of care). Always confirm the code in the tabular list: follow its Excludes1/Excludes2, “code first” and “use additional code” notes, and add a 7th character where required.

Source: CDC/NCHS ICD-10-CM FY2027 alphabetic index.