U0003 – Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, making use of high throughput technologies as described by cms-2020-01-r
HCPCS Level II code · U codes: Coronavirus Diagnostic Panel
HCPCS codeU0003
- Long description
- Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, making use of high throughput technologies as described by cms-2020-01-r
- Short description
- Cov-19 amp prb hgh thruput
- Pricing indicator
22Clinical Lab Fee Schedule – priced by carrier (gap-fill)- Medicare coverage
CCarrier judgment – coverage decided by the Medicare contractor- BETOS category
T1HLab tests - other (Non-Medicare fee schedule)- Added
- April 14, 2020
- Last change
- May 12, 2023 – No change
- Termination date
- May 11, 2023
Frequently asked questions
What is HCPCS code U0003?
U0003 is a HCPCS Level II code for infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, making use of high throughput technologies as described by cms-2020-01-r. It was discontinued on May 11, 2023.
Does Medicare cover U0003?
The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.
Nearby U codes
- U0001 – Cdc 2019 novel coronavirus (2019-ncov) real-time rt-pcr diagnostic panel
- U0002 – 2019-ncov coronavirus, sars-cov-2/2019-ncov (covid-19), any technique, multiple types or subtypes (includes all targets), non-cdc
- U0004 – 2019-ncov coronavirus, sars-cov-2/2019-ncov (covid-19), any technique, multiple types or subtypes (includes all targets), non-cdc, making use of high throughput technologies as described by cms-2020-01-r
- U0005 – Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc, making use of high throughput technologies, completed within 2 calendar days from date of specimen collection (list separately in addition to either hcpcs code u0003 or u0004) as described by cms-2020-01-r2
Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.