Q5159 – Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg
HCPCS Level II code · Q codes: Temporary Codes
HCPCS codeQ5159
- Long description
- Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg
- Short description
- Inj, denosumab-dssb, 1 mg
- Pricing indicator
51Drugs- Medicare coverage
CCarrier judgment – coverage decided by the Medicare contractor- BETOS category
O1DChemotherapy- Added
- October 1, 2025
- Last change
- October 1, 2025 – No change
Frequently asked questions
What is HCPCS code Q5159?
Q5159 is a HCPCS Level II code for injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg.
Does Medicare cover Q5159?
The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.
Nearby Q codes
- Q5151 – Injection, eculizumab-aagh (epysqli), biosimilar, 2 mg
- Q5152 – Injection, eculizumab-aeeb (bkemv), biosimilar, 2 mg
- Q5153 – Injection, aflibercept-yszy (opuviz), biosimilar, 1 mg
- Q5154 – Injection, omalizumab-igec (omlyclo), biosimilar, 5 mg
- Q5155 – Injection, aflibercept-jbvf (yesafili), biosimilar, 1 mg
- Q5156 – Injection, tocilizumab-anoh (avtozma), biosimilar, 1 mg
- Q5157 – Injection, denosumab-bmwo (stoboclo/osenvelt), biosimilar, 1 mg
- Q5158 – Injection, denosumab-bnht (bomyntra/conexxence), biosimilar, 1 mg
- Q5160 – Injection, bevacizumab-nwgd (jobevne), biosimilar, 10 mg
- Q5161 – Injection, denosumab-kyqq (aukelso/bosaya), biosimilar, 1 mg
- Q5162 – Injection, denosumab-nxxp (bildyos/bilprevda), biosimilar, 1 mg
- Q5164 – Injection, ustekinumab-hmny (starjemza), biosimilar, 1 mg
- Q5165 – Injection, denosumab-mobz (oziltus), biosimilar, 1 mg
- Q5166 – Injection, denosumab-desu (osvyrti/jubereq), biosimilar, 1 mg
- Q5167 – Injection, denosumab-qbde (enoby/xtrenbo), biosimilar, 1 mg
- Q5168 – Injection, ranibizumab-leyk (nufymco), biosimilar, 0.1 mg
Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.