Q4255 – Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)

HCPCS Level II code · Q codes: Temporary Codes

Active code Carrier judgment

HCPCS codeQ4255
Long description
Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)
Short description
Reguard, topical use per sq
Pricing indicator
11 Priced using national RVUs (Physician Fee Schedule)
Medicare coverage
C Carrier judgment – coverage decided by the Medicare contractor
BETOS category
O1E Other drugs
ASC
Approved for ambulatory surgical centers
Added
October 1, 2020
Last change
January 1, 2026 – No change

Frequently asked questions

What is HCPCS code Q4255?

Q4255 is a HCPCS Level II code for reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure).

Does Medicare cover Q4255?

The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.

Nearby Q codes

Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.