Q4222 – Progenamatrix, per square centimeter (add-on, list separately in addition to primary procedure)
HCPCS Level II code · Q codes: Temporary Codes
HCPCS codeQ4222
- Long description
- Progenamatrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Short description
- Progenamatrix, per sq cm
- Pricing indicator
11Priced using national RVUs (Physician Fee Schedule)- Medicare coverage
CCarrier judgment – coverage decided by the Medicare contractor- BETOS category
O1EOther drugs- ASC
- Approved for ambulatory surgical centers
- Added
- October 1, 2019
- Last change
- January 1, 2026 – No change
Frequently asked questions
What is HCPCS code Q4222?
Q4222 is a HCPCS Level II code for progenamatrix, per square centimeter (add-on, list separately in addition to primary procedure).
Does Medicare cover Q4222?
The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.
Nearby Q codes
- Q4214 – Cellesta cord, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4215 – Axolotl ambient or axolotl cryo, 0.1 mg
- Q4216 – Artacent cord, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4217 – Woundfix, biowound, woundfix plus, biowound plus, woundfix xplus or biowound xplus, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4218 – Surgicord, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4219 – Surgigraft-dual, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4220 – Bellacell hd or surederm, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4221 – Amniowrap2, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4223 – Dermabind sl optic, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4224 – Human health factor 10 amniotic patch (hhf10-p), per square centimeter (add-on, list separately in addition to primary procedure)
- Q4225 – Amniobind or dermabind tl, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4226 – Myown skin, includes harvesting and preparation procedures, per square centimeter
- Q4227 – Amniocore, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4228 – Bionextpatch, per square centimeter
- Q4229 – Cogenex amniotic membrane, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4230 – Cogenex flowable amnion, per 0.5 cc
Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.