Q0163 – Diphenhydramine hydrochloride, 50 mg, oral, fda approved prescription anti-emetic, for use as a complete therapeutic substitute for an iv anti-emetic at time of chemotherapy treatment not to exceed a 48 hour dosage regimen

HCPCS Level II code · Q codes: Temporary Codes

Active code Special coverage instructions apply

HCPCS codeQ0163
Long description
Diphenhydramine hydrochloride, 50 mg, oral, fda approved prescription anti-emetic, for use as a complete therapeutic substitute for an iv anti-emetic at time of chemotherapy treatment not to exceed a 48 hour dosage regimen
Short description
Diphenhydramine hcl 50mg
Pricing indicator
51 Drugs
Medicare coverage
D Special coverage instructions apply
BETOS category
O1D Chemotherapy
Added
April 1, 1998
Last change
April 1, 1998 – No change

Frequently asked questions

What is HCPCS code Q0163?

Q0163 is a HCPCS Level II code for diphenhydramine hydrochloride, 50 mg, oral, fda approved prescription anti-emetic, for use as a complete therapeutic substitute for an iv anti-emetic at time of chemotherapy treatment not to exceed a 48 hour dosage regimen.

Does Medicare cover Q0163?

The HCPCS file lists coverage code D: Special coverage instructions apply. Coverage and payment also depend on local coverage determinations and the patient’s plan.

Nearby Q codes

Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.