M0224 – Intravenous infusion, pemivibart, for the pre-exposure prophylaxis only, for certain adults and adolescents (12 years of age and older weighing at least 40 kg) with no known sars-cov-2 exposure, who either have moderate-to-severe immune compromise due to a medical condition or receipt of immunosuppressive medications or treatments, includes infusion and post administration monitoring

HCPCS Level II code · M codes: Medical Services and Quality Measures

Active code Carrier judgment

HCPCS codeM0224
Long description
Intravenous infusion, pemivibart, for the pre-exposure prophylaxis only, for certain adults and adolescents (12 years of age and older weighing at least 40 kg) with no known sars-cov-2 exposure, who either have moderate-to-severe immune compromise due to a medical condition or receipt of immunosuppressive medications or treatments, includes infusion and post administration monitoring
Short description
Pemivibart infusion
Pricing indicator
54 Vaccinations
Medicare coverage
C Carrier judgment – coverage decided by the Medicare contractor
BETOS category
O1G Immunizations/Vaccinations
Added
March 22, 2024
Last change
March 22, 2024 – No change

Frequently asked questions

What is HCPCS code M0224?

M0224 is a HCPCS Level II code for intravenous infusion, pemivibart, for the pre-exposure prophylaxis only, for certain adults and adolescents (12 years of age and older weighing at least 40 kg) with no known sars-cov-2 exposure, who either have moderate-to-severe immune compromise due to a medical condition or receipt of immunosuppressive medications or treatments, includes infusion and post administration monitoring.

Does Medicare cover M0224?

The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.

Nearby M codes

Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.