G8451 – Beta-blocker therapy for lvef <=40% not prescribed for reasons documented by the clinician (e.g., low blood pressure, fluid overload, asthma, patients recently treated with an intravenous positive inotropic agent, allergy, intolerance, other medical reasons, patient declined, other patient reasons)
HCPCS Level II code · G codes: Procedures / Professional Services (Temporary)
HCPCS codeG8451
- Long description
- Beta-blocker therapy for lvef <=40% not prescribed for reasons documented by the clinician (e.g., low blood pressure, fluid overload, asthma, patients recently treated with an intravenous positive inotropic agent, allergy, intolerance, other medical reasons, patient declined, other patient reasons)
- Short description
- Pt w/abn lvef inelig b-bloc
- Pricing indicator
00Not separately priced by Part B (bundled, not covered or Part A only)- Medicare coverage
CCarrier judgment – coverage decided by the Medicare contractor- BETOS category
M5DSpecialist - other- Added
- January 1, 2008
- Last change
- January 1, 2023 – No change
Frequently asked questions
What is HCPCS code G8451?
G8451 is a HCPCS Level II code for beta-blocker therapy for lvef <=40% not prescribed for reasons documented by the clinician (e.g., low blood pressure, fluid overload, asthma, patients recently treated with an intravenous positive inotropic agent, allergy, intolerance, other medical reasons, patient declined, other patient reasons).
Does Medicare cover G8451?
The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.
Nearby G codes
- G8427 – Eligible clinician attests to documenting in the medical record they obtained, updated, or reviewed the patient's current medications
- G8428 – Current list of medications not documented as obtained, updated, or reviewed by the eligible clinician, reason not given
- G8430 – Documentation of a medical reason(s) for not documenting, updating, or reviewing the patient's current medications list (e.g., patient is in an acute health crisis where time is of the essence and delay of treatment would jeopardize the patient's health status)
- G8431 – Screening for depression is documented as being positive and a follow-up plan is documented
- G8432 – Depression screening not documented, reason not given
- G8433 – Screening for depression not completed, documented patient or medical reason
- G8442 – Pain assessment not documented as being performed, documentation the patient is not eligible for a pain assessment using a standardized tool at the time of the encounter
- G8450 – Beta-blocker therapy prescribed
- G8452 – Beta-blocker therapy not prescribed
- G8458 – Clinician documented that patient is not an eligible candidate for genotype testing; patient not receiving antiviral treatment for hepatitis c during the measurement period (e.g. genotype test done prior to the reporting period, patient declines, patient not a candidate for antiviral treatment)
- G8460 – Clinician documented that patient is not an eligible candidate for quantitative rna testing at week 12; patient not receiving antiviral treatment for hepatitis c
- G8461 – Patient receiving antiviral treatment for hepatitis c during the measurement period
- G8464 – Clinician documented that prostate cancer patient is not an eligible candidate for adjuvant hormonal therapy; low or intermediate risk of recurrence or risk of recurrence not determined
- G8465 – High or very high risk of recurrence of prostate cancer
- G8473 – Angiotensin converting enzyme (ace) inhibitor or angiotensin receptor blocker (arb) therapy prescribed
- G8474 – Angiotensin converting enzyme (ace) inhibitor or angiotensin receptor blocker (arb) therapy not prescribed for reasons documented by the clinician (e.g., allergy, intolerance, pregnancy, renal failure due to ace inhibitor, diseases of the aortic or mitral valve, other medical reasons) or (e.g., patient declined, other patient reasons)
Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.