A4100 – Non-sheet form skin substitute, fda cleared as a device, not otherwise specified (list in addition to primary procedure)
HCPCS Level II code · A codes: Transportation, Medical & Surgical Supplies, Miscellaneous & Experimental
HCPCS codeA4100
- Long description
- Non-sheet form skin substitute, fda cleared as a device, not otherwise specified (list in addition to primary procedure)
- Short description
- Nosht skin sub fda clrd nos
- Pricing indicator
13Priced by the Medicare contractor (carrier)- Medicare coverage
CCarrier judgment – coverage decided by the Medicare contractor- BETOS category
P5AAmbulatory procedures - skin- Added
- April 1, 2022
- Last change
- January 1, 2026 – No change
Frequently asked questions
What is HCPCS code A4100?
A4100 is a HCPCS Level II code for non-sheet form skin substitute, fda cleared as a device, not otherwise specified (list in addition to primary procedure).
Does Medicare cover A4100?
The HCPCS file lists coverage code C: Carrier judgment – coverage decided by the Medicare contractor. Coverage and payment also depend on local coverage determinations and the patient’s plan.
Nearby A codes
- A2043 – Biobrane (add-on, list separately in addition to primary procedure), per square centimeter
- A2044 – Biobrane glove, each
- A2045 – Novashield or novogen wound matrix (add-on, list separately in addition to primary procedure), per square centimeter
- A2046 – Dermisphere hdrt, per square centimeter (add-on, list separately in addition to primary procedure)
- A2047 – Lacertamatrix, per square centimeter (add-on, list separately in addition to primary procedure)
- A2048 – Puraply mz, per milligram
- A2049 – Theracor, per square centimeter (add-on, list separately in addition to primary procedure)
- A2050 – Fibrillar collagen wound dressing, per milligram
- A4206 – Syringe with needle, sterile, 1 cc or less, each
- A4207 – Syringe with needle, sterile 2 cc, each
- A4208 – Syringe with needle, sterile 3 cc, each
- A4209 – Syringe with needle, sterile 5 cc or greater, each
- A4210 – Needle-free injection device, each
- A4211 – Supplies for self-administered injections
- A4212 – Non-coring needle or stylet with or without catheter
- A4213 – Syringe, sterile, 20 cc or greater, each
Source: CMS HCPCS Level II quarterly file, October 2026. Reference only – check payer policy before billing.